Evidence map›Paper›PMID 31235552›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

The Impact of TCR Signal Strength on Resident Memory T Cell Formation during Influenza Virus Infection.

Jessica K Fiege, Ian A Stone, Elizabeth J Fay, Matthew W Markman, Sathi Wijeyesinghe, Marissa G Macchietto, Steven Shen, David Masopust, Ryan A Langlois

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Origins of CD8 tissue resident memory.Frontiers in immunology · 2026
    Review
  5. Article
  6. Article
  7. A variational deep-learning approach to modeling memory T cell dynamics.bioRxiv : the preprint server for biology · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Tissue-Resident Memory T Cells in Allergy.Clinical reviews in allergy & immunology · 2024
    Review
  12. Antigen perception in T cells by long-term Erk and NFAT signaling dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Human T lymphocytes at tumor sites.Seminars in immunopathology · 2022
    Review
  15. Influenza-Induced CD103ImmunoHorizons · 2022
    Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jessica K FiegeDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-4129-8742
Ian A StoneDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-4929-4324
Elizabeth J FayDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455.
Matthew W MarkmanDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-3432-9854
Sathi WijeyesingheDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455.
Marissa G MacchiettoInstitute for Health Informatics, University of Minnesota, Minneapolis, MN 55455.
Steven ShenInstitute for Health Informatics, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0001-7725-1260
David MasopustDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455.
Ryan A LangloisDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455; langlois@umn.edu.
University of Minnesota · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
TRAINING-PULMONARY CELL &MOLECULAR BIOLOGY &PHYSIOLOGYT32HL007741 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUDLEY, R. ADAMS, INGBAR, DAVID H · 1994 to 2023
$13.9M
IMMUNOLOGY TRAINING PROGRAMT32AI007313 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Carla Rothlin · 1989 to 2026
$5.7M
Mechanisms and consequences of epithelial cell survival from influenza virus infection.R01AI132962 · NIAID · UNIVERSITY OF MINNESOTA · PI LANGLOIS, RYAN · 2017 to 2021
$2.3M
Harnessing microRNAs to explore influenza virus immunityK22AI110581 · NIAID · UNIVERSITY OF MINNESOTA · PI LANGLOIS, RYAN · 2015 to 2016
$270k
NCATS NIH HHS UL1 TR002494NCI NIH HHS P30 CA077598NHLBI NIH HHS T32 HL007741NIAID NIH HHS HHSN272201200005CNIAID NIH HHS HHSN272201400005CNIAID NIH HHS K22 AI110581NIAID NIH HHS R01 AI132962NIAID NIH HHS T32 AI007313
6 · The paper itself

Abstract

Resident memory T cells (T

Indexed as

AnimalsCell DifferentiationFemaleImmunologic MemoryInfluenza A virusMiceMice, Inbred C57BLOrthomyxoviridae InfectionsReceptors, Antigen, T-CellSignal TransductionT-Lymphocyte SubsetsReceptors, Antigen, T-Cell

Identifiers

PMID31235552
PMCPMC6684852
OpenAlexW2956132863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.