Evidence map›Paper›PMID 31234800›Full record

ArticleBMC microbiology2019

Rapidly disseminating bla

Chaitra Shankar, Purva Mathur, Manigandan Venkatesan, Agila Kumari Pragasam, Shalini Anandan, Surbhi Khurana, Balaji Veeraraghavan

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Systematic review of multidrug-resistantFrontiers in microbiology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Genomic characterization ofFrontiers in microbiology · 2026
    Article
  6. Article
  7. Characterization of OXA232-Producing Carbapenem-ResistantPolish journal of microbiology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Genomic Epidemiology of Carbapenem-ResistantAntimicrobial agents and chemotherapy · 2023
    Article
  14. Heteroresistance to Colistin in Clinical Isolates ofAntibiotics (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Diversity and Distribution ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chaitra ShankarDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Purva MathurDepartment of Laboratory Medicine JRNA Trauma Centre, All India Institute of Medical Sciences, New Delhi, India. purvamathur@yahoo.co.in.
Manigandan VenkatesanDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Agila Kumari PragasamDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Shalini AnandanDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Surbhi KhuranaDepartment of Laboratory Medicine JRNA Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Balaji VeeraraghavanDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Christian Medical College · INAll India Institute of Medical Sciences · INChristian Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, in India, there has been a shift from NDM to OXA48-like carbapenemases. OXA-181 and OXA-232 are the frequently produced variants of OXA48-like carbapenemases. OXA48-like carbapenemases are also known to be carried on transposons such as Tn1999, Tn1999.2 and it is also associated with IS1R carried on Tn1999. In India, there are no previous reports studying the association of mobile genetic elements (MGEs) with OXA48-like carbapenemases. The present study was aimed at determining the genetic backbone of OXA48-like carbapenemases to determine the role of MGEs in its transfer and to investigate the Inc plasmid type carrying bla

resultsA total of 49 carbapenem resistant K. pneumoniae which included 25 isolates from South India and 24 isolates from North India, were included in the study. Whole genome sequencing using Ion Torrent PGM was performed to study the isolates. OXA-232 was present in 35 isolates (71%). In 19 isolates (39%), bla

conclusionOXA-232 is the predominant variant of OXA48-like carbapenemase with ST231 being the commonest ST of OXA48-like carbapenemase producing K. pneumoniae in India. Diverse MGEs have been associated with both bla

Indexed as

DNA Transposable ElementsBacterial Proteinsbeta-LactamasesDNA, BacterialGenetic VariationHumansIndiaKlebsiella InfectionsKlebsiella pneumoniaePlasmidsWhole Genome SequencingBacterial Proteinsbeta-LactamasescarbapenemaseDNA, BacterialDNA Transposable Elementsbla OXA-232IndiaInsertion sequencesK. pneumoniaeST231Transposons

Identifiers

PMID31234800
PMCPMC6591861
OpenAlexW2952429017

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.