Evidence map›Paper›PMID 31234647›Full record

ArticleJournal of investigative medicine high impact case reports

A Rare Manifestation of a Rare Disease: Mantle Cell Lymphoma Presenting With Aseptic Meningitis.

Elvira Umyarova, Sreedhar Adapa, Srikanth Naramala, Vijay Gayam, Narothama Reddy Aeddula, Venu Madhav Konala

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Elvira Umyarova1 University of Vermont, Burlington, VT, USA.
Sreedhar Adapa2 Kaweah Delta Medical Center, Visalia, CA, USA.ORCID 0000-0001-5608-5654
Srikanth Naramala3 Adventist Medical Center Hanford, Hanford, CA, USA.
Vijay Gayam4 Interfaith Medical Center, Brooklyn, NY, USA.ORCID 0000-0001-5194-9134
Narothama Reddy Aeddula5 Deaconess Health System Inc, Evansville, IN, USA.
Venu Madhav Konala6 Ashland-Bellefonte Cancer Center, Ashland, KY, USA.ORCID 0000-0003-1953-8815
Adventist HealthCare · USAshland Bellefonte Cancer Center · USDeaconess Hospital · USInterfaith Medical Center · USKaweah Delta Health Care District · USUniversity of Vermont · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mantle cell lymphoma (MCL) is a rare form of non-Hodgkin lymphoma characterized by clonal proliferation of follicular mantle zone B lymphocytes. It is caused by abnormal chromosomal translocation t(11;14) resulting in aberrant expression of cyclin D1. This leads to activation of anti-apoptotic pathways and abnormal proliferation of MCL cells. Patients can present with an indolent course or a fulminant disease with short overall survival. The disease frequently involves extranodal organs, but rarely manifests with neurological symptoms. We report a rare case of aberrant CD5-negative MCL presenting with aseptic meningitis.

Indexed as

AdultAntigens, CD20Bone MarrowCerebrospinal FluidCyclin D1HumansImmunohistochemistryLymphoma, Mantle-CellMaleMeningitis, AsepticPancytopeniaRare DiseasesAntigens, CD20Cyclin D1aseptic meningitismantle cell lymphomaMIPI

Identifiers

PMID31234647
PMCPMC6593924
OpenAlexW2954275872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.