Evidence map›Paper›PMID 31234559›Full record

ArticleInternational journal of molecular sciences2019

Concentration of Fe(3+)-Triapine in BEAS-2B Cells.

William E Antholine, Charles R Myers

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

William E AntholineDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA. wantholi@mcw.edu.
Charles R MyersDepartment of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. cmyers@mcw.edu.
Medical College of Wisconsin · US

Funding

TR&D Project 3P41EB001980 · NIBIB · MEDICAL COLLEGE OF WISCONSIN · PI KLUG, CANDICE S · 2003 to 2017
$16.3M
National Institute of Biomedical Imaging and Bioengineering P41 EB001980NIBIB NIH HHS P41 EB001980
6 · The paper itself

Abstract

An electron paramagnetic resonance (EPR) method was used to determine the concentration of the antitumor agent Triapine in BEAS-2B cells when Triapine was bound to iron (Fe). Knowledge of the concentration of Fe-Triapine in tumor cells may be useful to adjust the administration of the drug or to adjust iron uptake in tumor cells. An EPR spectrum is obtained for Fe(3+)-Triapine, Fe(3+)(Tp)

Indexed as

Ascorbic AcidCells, CulturedElectron Spin Resonance SpectroscopyHumansIronPyridinesThiosemicarbazonesTransferrin3-aminopyridine-2-carboxaldehyde thiosemicarbazoneAscorbic AcidIronPyridinesThiosemicarbazonesTransferrinBEAS-2B bronchial epithelial cellselectron paramagnetic resonanceEPRTriapine

Identifiers

PMID31234559
PMCPMC6627071
OpenAlexW2951135490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.