Evidence map›Paper›PMID 31234532›Full record

ReviewMarine drugs2019

Metabolites of Seaweeds as Potential Agents for the Prevention and Therapy of Influenza Infection.

Natalia Besednova, Tatiana Zaporozhets, Tatiana Kuznetsova, Ilona Makarenkova, Lydmila Fedyanina, Sergey Kryzhanovsky, Olesya Malyarenko, Svetlana Ermakova

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Carrageenan of Red AlgaeMolecules (Basel, Switzerland) · 2022
    Article
  5. Review
  6. Experimental Evaluation of Food-Grade Semi-Refined Carrageenan Toxicity.International journal of molecular sciences · 2021
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Natalia BesednovaFederal State Budgetary Scientific Institution, Somov Research Institute of Epidemiology and Microbiology, Sel'skaya street, 1, Vladivostok 690087, Russia. besednoff_lev@mail.ru.
Tatiana ZaporozhetsFederal State Budgetary Scientific Institution, Somov Research Institute of Epidemiology and Microbiology, Sel'skaya street, 1, Vladivostok 690087, Russia. niiem_vl@mail.ru.
Tatiana KuznetsovaFederal State Budgetary Scientific Institution, Somov Research Institute of Epidemiology and Microbiology, Sel'skaya street, 1, Vladivostok 690087, Russia. takuznets@mail.ru.
Ilona MakarenkovaFederal State Budgetary Scientific Institution, Somov Research Institute of Epidemiology and Microbiology, Sel'skaya street, 1, Vladivostok 690087, Russia. ilona_m@mail.ru.ORCID 0000-0001-6450-840X
Lydmila FedyaninaFar Eastern Federal University, School of Biomedicine, bldg. M25 FEFU Campus, Ajax Bay, Russky Isl., Vladivostok 690922, Russia. fedyanina.ln@dvfu.ru.
Sergey KryzhanovskyFar Eastern Federal University, School of Biomedicine, bldg. M25 FEFU Campus, Ajax Bay, Russky Isl., Vladivostok 690922, Russia. kryzhanovskii.sp@dvfu.ru.
Olesya MalyarenkoG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Pr. 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia. malyarenko.os@gmail.com.
Svetlana ErmakovaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Pr. 100-letiya Vladivostoka, 159, Vladivostok 690022, Russia. ermakova@piboc.dvo.ru.
Vladivostok State Medical University · RUFar Eastern Federal University · RUPacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RU

Funding

Far East Branch, Russian Academy of Sciences 18-5-084
6 · The paper itself

Abstract

contextSeaweed metabolites (fucoidans, carrageenans, ulvans, lectins, and polyphenols) are biologically active compounds that target proteins or genes of the influenza virus and host components that are necessary for replication and reproduction of the virus.

objectiveThis review gathers the information available in the literature regarding to the useful properties of seaweeds metabolites as potential agents for the prevention and therapy of influenza infection. MATERIALS AND

methodsThe sources of scientific literature were found in various electronic databases (i.e., PubMed, Web of Science, and ScienceDirect) and library search. The retrospective search depth is 25 years.

resultsInfluenza is a serious medical and social problem for humanity. Recently developed drugs are quite effective against currently circulating influenza virus strains, but their use can lead to the selection of resistant viral strains. In this regard, new therapeutic approaches and drugs with a broad spectrum of activity are needed. Metabolites of seaweeds fulfill these requirements. This review presents the results of in vitro and in vivo experimental and clinical studies about the effectiveness of these compounds in combating influenza infection and explains the necessity of their use as a potential basis for the creation of new drugs with a broad spectrum of activity.

Indexed as

AnimalsAntiviral AgentsCarrageenanHumansInfluenza, HumanOrthomyxoviridae InfectionsPolyphenolsRetrospective StudiesSeaweedAntiviral AgentsCarrageenanPolyphenolsalgaalginatesanti-viral activityFlulectinspolyphenolssulphated polysaccharides

Identifiers

PMID31234532
PMCPMC6627559
OpenAlexW2951777611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.