Evidence map›Paper›PMID 31234518›Full record

ArticleJournal of clinical medicine2019

25-Hydroxy Vitamin D Detection Using Different Analytic Methods in Patients with Migraine.

Luca Gallelli, Andzelika Michniewicz, Erika Cione, Aida Squillace, Manuela Colosimo, Corrado Pelaia, Alessia Fazio, Stefania Zampogna, Francesco Peltrone, Rosario Iannacchero and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Determination of AGE-CML Level in Commercially Available Sports Bar in Italy.Recent advances in food, nutrition & agriculture · 2025
    Article
  5. Article
  6. Review
  7. Observational
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Luca GallelliDepartment of Health Science University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, Italy. gallelli@unicz.it.ORCID 0000-0003-0858-7902
Andzelika MichniewiczDepartment of Health Science University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, Italy. angymich@unicz.it.
Erika CioneDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende Cosenza, Italy. erika.cione@unical.it.
Aida SquillaceDepartment of Health Science University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, Italy. aidasquillace@libero.it.
Manuela ColosimoDepartment of Health Science University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, Italy. manuelacolosimo@hotmail.it.
Corrado PelaiaDepartment of Health Science University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, Italy. pelaia.corrado@gmail.com.
Alessia FazioDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende Cosenza, Italy. alessia.fazio@unical.it.
Stefania ZampognaDepartment of Pediatry, "Pugliese-Ciaccio" Hospital, 88100 Catanzaro, Italy. stezampogna@gmail.com.
Francesco PeltroneDepartment of Pediatry, "Pugliese-Ciaccio" Hospital, 88100 Catanzaro, Italy. f.peltrone@libero.it.
Rosario IannaccheroDepartment of Neurology, "Pugliese-Ciaccio" Hospital, 88100 Catanzaro, Italy. rosarioiann@tiscali.it.
Giovambattista De SarroDepartment of Health Science University of Catanzaro and Operative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, Italy. desarro@unicz.it.
G Amp Sp Working GroupG&SP Working Group enclosed: Giuseppe Giuliano, Giacomo Leuzzi, Antonio Scuteri, Antonio Guerra, and Francesco Corasaniti (Azienda Sanitaria Provinciale, 88100 Catanzaro, Italy), Piero Vasapollo (Azienda Sanitaria Provinciale, 88900 Crotone, Italy), Vincenzo Natale and Nazareno Brissa (Azienda Sanitaria Provinciale, 89900 Vibo Valentia, Italy).
Monica SalernoForensic Medicine, Department of Medical Science, Surgical Science and advanced Technologies "G.F. Ingrassia", University of Catania, 95124 Catania, Italy. monica.salerno@unict.it.
Giulio Di MizioForensic Medicine, Department of Law, Economy and Sociology, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy. giulio.dimizio@unicz.it.ORCID 0000-0001-7279-3693
Azienda Ospedaliero Universitario Mater Domini · ITAzienda Ospedaliera Pugliese Ciaccio · ITMagna Graecia University · ITUniversity of Calabria · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the performance of different analytic methods, such as liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), high-performance liquid chromatography-ultraviolet (HPLC-UV), enzyme-linked immunosorbent assay (EIA), and chemiluminescence immunoassays (CLIA), in order to highlight whether or not there is relative superiority amongst the assays. We analyzed two groups of subjects suffering from headache and two groups of healthy subjects. DESIGN AND

methodsWe performed a prospective, single-blind single-center control-group study on 220 subjects with migraine. Subjects of both sexes >10 years old and with 12 months' history of migraine were eligible for the study. As a control group, 120 healthy subjects were chosen by their family physician.

resultsLC-MS/MS evaluation documented that in all enrolled subjects (migraine and control groups), the serum vitamin D3 levels were lower with respect to the normal range (30-100 ng/mL), with a mean value of 15.4 ng/mL, without difference between sex. The mean values measured using HPLC-UV, EIA, and CLIA tests such as Liaison

conclusionsIn conclusion, the population generally has low values of the vitamin D3 hormone, and the suggested range should probably be revised. HPLC-UV and CLIA were found to have appropriate analytical values compared to the reference method (LC-MS/MS), so it is possible to suggest their routine use to optimize care.

Indexed as

CLIAclinical risk managementEIAheadacheHPLC-UVLC-MS/MSvitamin D

Identifiers

PMID31234518
PMCPMC6617382
OpenAlexW2952804558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.