Evidence map›Paper›PMID 31234456›Full record

ArticleMarine drugs2019

Steroids from Marine-Derived Fungi: Evaluation of Antiproliferative and Antimicrobial Activities of Eburicol.

Ana Camila Dos Santos Dias, Aurélie Couzinet-Mossion, Nicolas Ruiz, Fatima Lakhdar, Samira Etahiri, Samuel Bertrand, Lucie Ory, Christos Roussakis, Yves François Pouchus, El-Hassane Nazih and 1 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. The GenusMolecules (Basel, Switzerland) · 2021
    Review
  8. Metabolites fromJournal of fungi (Basel, Switzerland) · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ana Camila Dos Santos DiasFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. acamiladias@gmail.com.
Aurélie Couzinet-MossionFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. aurelie.couzinet-mossion@univ-nantes.fr.ORCID 0000-0002-8391-8938
Nicolas RuizFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. nicolas.ruiz@univ-nantes.fr.ORCID 0000-0001-7330-4679
Fatima LakhdarLaboratory of Marine Biotechnology and Environment, Faculty of Science, University Chouaib Doukkali, BP 20 El Jadida, Morocco. fatima19862008@hotmail.fr.
Samira EtahiriLaboratory of Marine Biotechnology and Environment, Faculty of Science, University Chouaib Doukkali, BP 20 El Jadida, Morocco. setahiri@hotmail.com.
Samuel BertrandFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. samuel.bertrand@univ-nantes.fr.ORCID 0000-0002-5934-7012
Lucie OryFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. lucie.ory@etu.univ-nantes.fr.
Christos RoussakisFaculty of Pharmacy, University of Nantes, IICiMed, 9, Rue Bias, 44000 Nantes, France. christos.roussakis@univ-nantes.fr.
Yves François PouchusFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. yves-francois.pouchus@univ-nantes.fr.
El-Hassane NazihFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. el-hassane.nazih@univ-nantes.fr.
Gaetane Wielgosz-CollinFaculty of Pharmacy, University of Nantes, MMS-EA2160; 9, Rue Bias, 44000 Nantes, France. gaetane.wielgosz-collin@univ-nantes.fr.
Nantes Université · FRChouaib Doukkali University · MACibles et Médicaments des Infections et de l'Immunité

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior DF70040-020
6 · The paper itself

Abstract

The most common sterol in fungi is ergosterol, which has frequently been investigated in human pathogenic fungal strains. This sterol, and others isolated from fungal strains, has also demonstrated cytotoxicity against cancer cell lines and antimicrobial activities. Marine fungi can produce high amounts of bioactive compounds. So, a screening was performed to study sterol composition using GC/MS in 19 marine fungal strains and ergosterol was always the major one. One strain,

Indexed as

A549 CellsAnti-Infective AgentsAquatic OrganismsBacteriaCell Line, TumorCell ProliferationFungiHumansLanosterolMCF-7 CellsMicrobial Sensitivity TestsSteroidsAnti-Infective AgentsebericolLanosterolSteroidsantibacterial activityClonostachys roseacytotoxicityeburicolmarine fungisterol

Identifiers

PMID31234456
PMCPMC6628047
OpenAlexW2949237322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.