Evidence map›Paper›PMID 31234394›Full record

ReviewPharmaceutics2019

Nanoparticle- and Nanoporous-Membrane-Mediated Delivery of Therapeutics.

Mostafa Mabrouk, Rajakumari Rajendran, Islam E Soliman, Mohamed M Ashour, Hanan H Beherei, Khairy M Tohamy, Sabu Thomas, Nandakumar Kalarikkal, Gangasalam Arthanareeswaran, Diganta B Das

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mostafa MabroukRefractories, Ceramics and Building Materials Department, National Research Centre, 33 El Bohouth St (former EL Tahrirst)-Dokki, Giza 12622, Egypt. mostafamabrouk.nrc@gmail.com.ORCID 0000-0003-3330-6762
Rajakumari RajendranInternational and Inter-University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India. rajimpharm@gmail.com.
Islam E SolimanBiophysics Branch, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt. islam_biophysics@yahoo.com.ORCID 0000-0003-2934-1231
Mohamed M AshourFaculty of Engineering, Badr University, Cairo 11829, Egypt. mohamedashour739@gmail.com.
Hanan H BehereiRefractories, Ceramics and Building Materials Department, National Research Centre, 33 El Bohouth St (former EL Tahrirst)-Dokki, Giza 12622, Egypt. hananh.beherei@gmail.com.
Khairy M TohamyBiophysics Branch, Faculty of Science, Al-Azhar University, Cairo 11884, Egypt. already_a555@yahoo.com.
Sabu ThomasInternational and Inter-University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India. sabuthomas@mgu.ac.in.
Nandakumar KalarikkalInternational and Inter-University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala 686560, India. nkkalarikkal@mgu.ac.in.
Gangasalam ArthanareeswaranDepartment of Chemical Engineering, National Institute of Technology, Tiruchirappalli 620015, India. arthanareeg@nitt.edu.
Diganta B DasDepartment of Chemical Engineering, Loughborough University, Loughborough LE113TU, UK. D.B.Das@lboro.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceutical particulates and membranes possess promising prospects for delivering drugs and bioactive molecules with the potential to improve drug delivery strategies like sustained and controlled release. For example, inorganic-based nanoparticles such as silica-, titanium-, zirconia-, calcium-, and carbon-based nanomaterials with dimensions smaller than 100 nm have been extensively developed for biomedical applications. Furthermore, inorganic nanoparticles possess magnetic, optical, and electrical properties, which make them suitable for various therapeutic applications including targeting, diagnosis, and drug delivery. Their properties may also be tuned by controlling different parameters, e.g., particle size, shape, surface functionalization, and interactions among them. In a similar fashion, membranes have several functions which are useful in sensing, sorting, imaging, separating, and releasing bioactive or drug molecules. Engineered membranes have been developed for their usage in controlled drug delivery devices. The latest advancement in the technology is therefore made possible to regulate the physico-chemical properties of the membrane pores, which enables the control of drug delivery. The current review aims to highlight the role of both pharmaceutical particulates and membranes over the last fifteen years based on their preparation method, size, shape, surface functionalization, and drug delivery potential.

Indexed as

bioactive moleculesbio-imagingdrug delivery systemsmembranespharmaceutical particulates

Identifiers

PMID31234394
PMCPMC6631283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.