Evidence map›Paper›PMID 31234349›Full record

ArticleJournal of clinical medicine2019

Saliva and Serum Immune Responses in Apical Periodontitis.

Milla Pietiäinen, John M Liljestrand, Ramin Akhi, Kåre Buhlin, Anders Johansson, Susanna Paju, Aino Salminen, Päivi Mäntylä, Juha Sinisalo, Leo Tjäderhane and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Milla PietiäinenOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. milla.pietiainen@helsinki.fi.ORCID 0000-0002-4875-0682
John M LiljestrandOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. john.liljestrand@helsinki.fi.ORCID 0000-0001-6562-2458
Ramin AkhiMedical Microbiology and Immunology, Research Unit of Biomedicine, University of Oulu, FI-90014 Oulu, Finland. ramin.akhi@oulu.fi.
Kåre BuhlinOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. kare.buhlin@ki.se.
Anders JohanssonDepartment of Odontology, Molecular Periodontology Research, Umeå University, S-901 87 Umeå, Sweden. anders.p.johansson@umu.se.ORCID 0000-0002-8069-8263
Susanna PajuOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. susanna.paju@helsinki.fi.
Aino SalminenOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. aino.m.salminen@helsinki.fi.
Päivi MäntyläInstitute of Dentistry, University of Eastern Finland, FI-70211 Kuopio, Finland. paivi.mantyla@uef.fi.
Juha SinisaloHUCH Heart and Lung Center, Helsinki University Hospital, FI-00029 Helsinki, Finland. juha.sinisalo@hus.fi.ORCID 0000-0002-0169-5137
Leo TjäderhaneOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. leo.tjaderhane@helsinki.fi.
Sohvi HörkköMedical Microbiology and Immunology, Research Unit of Biomedicine, University of Oulu, FI-90014 Oulu, Finland. sohvi.horkko@nordlab.fi.
Pirkko J PussinenOral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, FI-00014 Helsinki, Finland. pirkko.pussinen@helsinki.fi.
University of Helsinki · FIOulu University Hospital · FIHelsinki University Hospital · FIUmeå University · SEUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apical periodontitis is an inflammatory reaction at the apex of an infected tooth. Its microbiota resembles that of marginal periodontitis and may induce local and systemic antibodies binding to bacteria- and host-derived epitopes. Our aim was to investigate the features of the adaptive immune response in apical periodontitis. The present Parogene cohort (

Indexed as

adaptive immunityantibodyapical periodontitissalivaserum

Identifiers

PMID31234349
PMCPMC6617293
OpenAlexW2949530881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.