Evidence map›Paper›PMID 31234337›Full record

ArticleMolecules (Basel, Switzerland)2019

Molecular Informatics Studies of the Iron-Dependent Regulator (ideR) Reveal Potential Novel Anti-

Samuel K Kwofie, Kweku S Enninful, Jaleel A Yussif, Lina A Asante, Mavis Adjei, Kwabena Kan-Dapaah, Elvis K Tiburu, Wilhelmina A Mensah, Whelton A Miller, Lydia Mosi and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. TargetingRSC medicinal chemistry · 2023
    Review
  4. The molecular mechanisms of the bacterial iron sensor IdeR.Biochemical Society transactions · 2023
    Article
  5. The Iron Response ofFrontiers in cellular and infection microbiology · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Samuel K KwofieDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. skkwofie@ug.edu.gh.
Kweku S EnninfulDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. kenninful@noguchi.ug.edu.gh.
Jaleel A YussifDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. jaleela96@yahoo.com.
Lina A AsanteDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. linaagyekumwaaa@gmail.com.
Mavis AdjeiDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. madjei008@st.ug.edu.gh.
Kwabena Kan-DapaahDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. kkan-dapaah@ug.edu.gh.
Elvis K TiburuDepartment of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. etiburu@ug.edu.gh.
Wilhelmina A MensahWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. wamensah@gmail.com.
Whelton A MillerDepartment of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA. wheltonm@seas.upenn.edu.
Lydia MosiWest African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Legon P.O. Box LG 54, Accra, Ghana. lmosi@ug.edu.gh.
Michael D WilsonDepartment of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA. Mwilson@noguchi.ug.edu.gh.
University of Ghana · GHLoyola University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buruli ulcer is a neglected tropical disease caused by the bacterium

Indexed as

Bacterial ProteinsBinding SitesBiological ProductsBuruli UlcerComputational BiologyHumansKineticsMolecular Docking SimulationMolecular Dynamics SimulationMycobacterium tuberculosisMycobacterium ulceransRepressor ProteinsBacterial ProteinsBiological ProductsIdeR protein, Mycobacterium tuberculosisRepressor Proteinsburuli ulcerDNA–binding siteiron dependent regulator (ideR)metal binding sitemolecular dockingmolecular dynamics simulationMycobacterium ulceransnatural product compounds

Identifiers

PMID31234337
PMCPMC6631925
OpenAlexW2949061294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.