Evidence map›Paper›PMID 31234333›Full record

ArticleBiomolecules2019

LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog,

Bin Li, Peng Lyu, Shuping Xie, Haixin Qin, Wenyuan Pu, Houxi Xu, Tianbao Chen, Chris Shaw, Lilin Ge, Hang Fai Kwok

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  8. Article
  9. Article
  10. Anti-Cancer Peptides: Status and Future Prospects.Molecules (Basel, Switzerland) · 2023
    Review
  11. Discovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion ofComputational and structural biotechnology journal · 2023
    Article
  12. Bioactive peptides for anticancer therapies.Biomaterials translational · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Antimicrobials from Venomous Animals: An Overview.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Bin LiJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210000, China. bli0503@163.com.
Peng LyuCancer Centre, Faculty of Health Sciences, University of Macau, Avenida de Universidade, Taipa, Macau SAR, China. penglyu00@163.com.
Shuping XieJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210000, China. shupingxie@outlook.com.
Haixin QinJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210000, China. haixin0831@126.com.
Wenyuan PuJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210000, China. wenyuanpu@foxmail.com.
Houxi XuJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210000, China. houxixu@126.com.
Tianbao ChenNatural Peptide Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. t.chen@qub.ac.uk.ORCID 0000-0001-8011-9260
Chris ShawNatural Peptide Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. chris.shaw@qub.ac.uk.
Lilin GeJiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Qixia District, Nanjing 210000, China. gelilin@njucm.edu.cn.
Hang Fai KwokCancer Centre, Faculty of Health Sciences, University of Macau, Avenida de Universidade, Taipa, Macau SAR, China. hfkwok@um.edu.mo.ORCID 0000-0002-6349-4517
Nanjing University of Chinese Medicine · CNQueen's University Belfast · GBUniversity of Macau · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphibians are a natural source of abundant antimicrobial peptides and thus have been widely investigated for isolation of such biomolecules. Many new antimicrobial peptide families have been discovered from amphibians. In this study, a novel antimicrobial peptide named

Indexed as

AnuraAmino Acid SequenceAmphibian ProteinsAnimalsAntimicrobial Cationic PeptidesCandida albicansCell Line, TumorEscherichia coliHumansInhibitory Concentration 50SkinStaphylococcus aureusAmphibian ProteinsAntimicrobial Cationic Peptidesamphibiananticancer peptideantimicrobial peptidesBrevinin-like peptidedrug discovery

Identifiers

PMID31234333
PMCPMC6627297
OpenAlexW2951988639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.