ArticlePediatric research2019
Cerebral oxygenation and blood flow in normal term infants at rest measured by a hybrid near-infrared device (BabyLux).
Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Noninvasive diffuse optical monitoring of cerebral blood flow and oxygenation responses to intermittent hypoxia in neonatal rats.Journal of biomedical optics · 2026Article
- Reproducibility of a time-resolved NIRS, multidistance diffuse correlation spectroscopy system: towards noninvasive longitudinal neuromonitoring.Neurophotonics · 2026Article
- Future perspectives of heart rate and oxygenation monitoring in the neonatal intensive care unit - a narrative review.Journal of clinical monitoring and computing · 2025Review
- Cortical activation and functional connectivity during different attention tasks using functional near-infrared spectroscopy in middle-aged and elderly people.European journal of medical research · 2025Article
- Effects of red blood cell transfusion on cerebral hemodynamics of preterm neonates.Neurophotonics · 2024Article
- Wearable fiber-free optical sensor for continuous monitoring of neonatal cerebral blood flow and oxygenation.Pediatric research · 2024Article
- Chassis-based fiber-coupled optical probe design for reproducible quantitative diffuse optical spectroscopy measurements.PloS one · 2024Article
- Assessment of power spectral density of microvascular hemodynamics in skeletal muscles at very low and low-frequency via near-infrared diffuse optical spectroscopies.Biomedical optics express · 2023Article
- Cerebrovascular reactivity to carbon dioxide tension in newborns: data from combined time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy.Neurophotonics · 2023Article
- Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study.Neurophotonics · 2022Article
- Dedicated near-infrared oximeter to monitor oxygenation in the superior sagittal sinus in newborn infants: a research agenda.Journal of biomedical optics · 2022Article
- Assessing cerebral blood flow, oxygenation and cytochrome c oxidase stability in preterm infants during the first 3 days after birth.Scientific reports · 2022Article
- Dynamics of cortical oxygenation during immediate adaptation to extrauterine life.Scientific reports · 2021Article
- The future of noninvasive neonatal brain assessment: the measure of cerebral blood flow by diffuse correlation spectroscopy in combination with near-infrared spectroscopy oximetry.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Foetal growth, birth transition, enteral nutrition and brain light scattering.Scientific reports · 2021Article
- Precision of time-resolved near-infrared spectroscopy-based measurements of cerebral oxygenation in preterm infants.Neurophotonics · 2021Article
- Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision.Biomedical optics express · 2021Article
- Cerebral Oximetry in Preterm Infants-To Use or Not to Use, That Is the Question.Frontiers in pediatrics · 2021Article
- Critical Closing Pressure by Diffuse Correlation Spectroscopy in a Neonatal Piglet Model.Acta neurochirurgica. Supplement · 2021Article
- Wearable and wireless time-domain near-infrared spectroscopy system for brain and muscle hemodynamic monitoring.Biomedical optics express · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe BabyLux device is a prototype optical neuro-monitor of cerebral oxygenation and blood flow for neonatology integrating time-resolved reflectance spectroscopy and diffuse correlation spectroscopy.
methodsHere we report the variability of six consecutive 30 s measurements performed in 27 healthy term infants at rest. Poor data quality excluded four infants.
resultsMean cerebral oxygenation was 59.6 ± 8.0%, with intra-subject standard deviation of 3.4%, that is, coefficient of variation (CV) of 5.7%. The inter-subject CV was 13.5%. Mean blood flow index was 2.7 × 10
conclusionThe intra-subject variability for cerebral oxygenation variability was improved compared to spatially resolved spectroscopy devices, while for the blood flow index it was comparable to that of other modalities for estimating cerebral blood flow in newborn infants. Most importantly, the simultaneous measurement of oxygenation and flow allows for interpretation of the high inter-subject variability of cerebral blood flow as being due to error of measurement rather than to physiological instability.
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