Observational studyObesity facts2019
Frequency of Hypoglycaemia after Different Bariatric Surgical Procedures.
Observational study in Obesity facts, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Incidence and risk factors of post-metabolic and bariatric surgery hypoglycemia: a systematic review.International journal of obesity (2005) · 2025Pooled it
- Postprandial plasma GLP-1 levels are elevated in individuals with postprandial hypoglycaemia following Roux-en-Y gastric bypass - a systematic review.Reviews in endocrine & metabolic disorders · 2023Pooled it
- Hypoglycemia in Pregnancies Following Gastric Bypass-a Systematic Review and Meta-analysis.Obesity surgery · 2022Pooled it
- PREVENT: A Randomized, Placebo-controlled Crossover Trial of Avexitide for Treatment of Postbariatric Hypoglycemia.The Journal of clinical endocrinology and metabolism · 2021Trial
- Sleeve gastrectomy for morbid obesity: weight loss trajectory and failure predictors over a decade.Future science OA · 2025Article
- Surgical or medical treatment of obesity-associated type 2 diabetes-an increasing clinical conundrum.World journal of diabetes · 2024Article
- Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia.Endocrine connections · 2024Review
- [Postoperative management].Wiener klinische Wochenschrift · 2023Article
- Benefits and Risks of Bariatric Surgery on Women's Reproductive Health: a Narrative Review.Obesity surgery · 2023Review
- Counter-regulatory responses to postprandial hypoglycaemia in patients with post-bariatric hypoglycaemia vs surgical and non-surgical control individuals.Diabetologia · 2023Article
- Post-Bariatric Hypoglycemia Is Associated with Endothelial Dysfunction and Increased Oxidative Stress.Biomedicines · 2022Article
- Beyond diabetes remission a step further: Post bariatric surgery hypoglycemia.World journal of diabetes · 2022Article
- The Bariatric-Metabolic Physician's Role in Managing Clinically Severe Obesity.Current obesity reports · 2021Review
- Predictors of Postprandial Hypoglycemia After Gastric Bypass Surgery: a Retrospective Case-Control Study.Obesity surgery · 2021Article
- Potential contribution of the gut microbiota to hypoglycemia after gastric bypass surgery.Chinese medical journal · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe frequency of postprandial hypoglycaemia after different operative procedures of bariatric surgery (BS) is unknown, although this complication is potentially dangerous. Predictors and severity of hypoglycaemia after Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy, and gastric banding were investigated in a large prospective study.
methodsThis study was performed at an excellence centre for BS at a tertiary care institution. Data of 333 patients (mean BMI: 44.9 ± 9.6 kg/m2; mean age: 40 ± 10 years; 80.7% women) were analysed in a prospective study with a 2-year observation period after BS. All patients underwent a 2-hour oral glucose tolerance test (OGTT) with measurements of blood glucose (BG) and insulin. For the purpose of this study, hypoglycaemia was defined as a post-challenge BG <2.8 mmol/L during the OGTT.
results72 (25.6%) of 281 patients showed post-challenge hypoglycaemia after surgery. Hypoglycaemia was different after various procedures: 32.6% of patients after RYGB, 22.6% after sleeve gastrectomy, but only 2.3% after gastric banding had hypoglycaemia. In the whole group, patients with hypoglycaemia had lost more weight (p = 0.013), had a slightly greater decrease in BMI (p = 0.037), a greater change in 2-hour post-challenge BG (p = 0.001), and a smaller change in 1-hour post-challenge insulin (p = 0.004) compared to patients without hypoglycaemia.
conclusionThis prospective study shows a higher prevalence of severe hypoglycaemia (25.6%) after BS than anticipated from retrospective registers. A systematic evaluation of glucose and insulin levels by OGTT 2 years post-surgery may help to identify patients at increased risk for symptomatic and asymptomatic hypoglycaemia.
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