Evidence map›Paper›PMID 31234015›Full record

ArticleRedox biology2019

The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide.

Yuxun Zhang, Sivakama S Bharathi, Megan E Beck, Eric S Goetzman

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 66 citations in OpenAlex.

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  18. Complex II Biology in Aging, Health, and Disease.Antioxidants (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yuxun ZhangDepartment of Pediatrics, Division of Medical Genetics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.
Sivakama S BharathiDepartment of Pediatrics, Division of Medical Genetics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.
Megan E BeckDepartment of Pediatrics, Division of Medical Genetics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.
Eric S GoetzmanDepartment of Pediatrics, Division of Medical Genetics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA. Electronic address: eric.goetzman@chp.edu.
Children's Hospital of Pittsburgh · USUniversity of Pittsburgh · US

Funding

Regulation of Peroxisomal Metabolism by Lysine AcylationR01DK090242 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOETZMAN, ERIC S · 2011 to 2024
$5.4M
NIDDK NIH HHS R01 DK090242
6 · The paper itself

Abstract

Fatty acid oxidation (FAO)-driven H

Indexed as

Acyl-CoA Dehydrogenase, Long-ChainAcyl-CoA OxidaseAnimalsCloning, MolecularEscherichia coliFatty AcidsGene ExpressionGenetic VectorsHep G2 CellsHumansHydrogen PeroxideIsoenzymesKidneyKineticsLiverLungAcyl-CoA Dehydrogenase, Long-ChainAcyl-CoA OxidaseFatty AcidsHydrogen PeroxideIsoenzymesRecombinant ProteinsHydrogen peroxide/mitochondria/fatty acid oxidation/acyl-CoA dehydrogenase

Identifiers

PMID31234015
PMCPMC6597861
OpenAlexW2951689345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.