Evidence map›Paper›PMID 31233069›Full record

SynthesisThe journal of nutrition, health & aging2019

Exercise Interventions for the Prevention and Treatment of Sarcopenia. A Systematic Umbrella Review.

D Beckwée, A Delaere, S Aelbrecht, V Baert, C Beaudart, O Bruyere, M de Saint-Hubert, I Bautmans

3 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The journal of nutrition, health & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 179 papers, 26 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed, 26 pooled it
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06823739 nacompletednot on this mapstarted 2020, after this paper: background citation

Personalized Diet with or Without Physical Exercise Improves Nutritional Status, Muscle Strength, Physical Performance and Quality of Life in Malnourished Older Adult Patients: a Prospec-tive Randomized Controlled Study

TypeinterventionalSponsorIstanbul UniversityRan2020 to 2020Enrolled20ConditionsMalnourished Elderly, Quality of Life (QOL), BMI, Hand Grip StrengthArmsExercise
NCT07253714 nacompletednot on this mapstarted 2024, after this paper: background citation

The effect of proprioceptive exercise training on cervical proprioception, kinesiophobia, and pain catastrophizing levels in sarcopenic geriatric individuals residing in nursing homes

TypeinterventionalSponsorAtılım UniversityRan2024 to 2024Enrolled31ConditionsSarcopenia in ElderlyArmsClassic exercises, Proprioceptive exercise training
NCT07572851 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care

TypeobservationalSponsorUniversity of VigoRan2026 to 2026Enrolled56ConditionsFrail Elderly, Fall RiskArmsMulticomponent Exercise Program- 1 times per week., Multicomponent Exercise Program- 2 times per week.
3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 26 syntheses or guidelines pooled it, 311 citations in OpenAlex.

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119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

D BeckwéeIvan Bautmans, Gerontology (GERO) and Frailty in Ageing research (FRIA) departments, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, B-1090 Brussels, Belgium, Email address: ivan.bautmans@vub.be, Phone number: +32 2 477 42 07.
A Delaere
S Aelbrecht
V Baert
C Beaudart
O Bruyere
M de Saint-Hubert
I Bautmans
Vrije Universiteit Brussel · BEUniversity of Liège · BECHU Dinant Godinne UCL Namur · BESOMT University of Physiotherapy · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this systematic review is to provide an overview of the efficacy of different exercise interventions to counter sarcopenia in older adults. This review will allow the Belgian Society of Gerontology and Geriatrics and other scientific societies to formulate specific exercise recommendations in their Clinical Guidelines for Sarcopenia.

designWe used the method of a systematic umbrella-review. Based on the level of evidence, we formulated specific recommendations for clinical practice.

methodsTwo databases (Pubmed and Web Of Science) were searched systematically and methodological quality of the reviews was assessed. Extracted data was than mapped to an exercise category and an overall synthesis (bottom line statements) was formulated for each of these exercise categories. Subsequently, we assigned a rating of the quality of the evidence supporting each bottom line statement.

resultsWe identified 14 systematic reviews or meta-analyses, encompassing four exercise categories: resistance training, resistance training + nutritional supplementation, multimodal exercise programmes and bloodflow restriction training. Importantly, very few systematic reviews or meta-analyses clearly mentioned baseline sarcopenia status. There is high quality evidence for a positive and significant effect of resistance training on muscle mass, muscle strength, and physical performance. The added effect of nutritional supplementation for resistance training on muscle function appears limited. Blood flow restriction training is a novel training method that has a significant impact on muscle strength.

conclusionSince sarcopenia is affecting all skeletal muscles in the body, we recommend training the large muscle groups in a total body approach. Although low-intensity resistance training (≤50% 1RM) is sufficient to induce strength gains, we recommend a high-intensity resistance training program (i.e. 80% 1RM) to obtain maximal strength gains. Multimodal exercises and blood flow restriction resistance training may be considered as well.

Indexed as

AgedExerciseExercise TherapyHumansSarcopeniaExercisemuscle massmuscle strengthphysical performancesarcopenia

Identifiers

PMID31233069
PMCPMC12280365
OpenAlexW2941075934

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.