Evidence map›Paper›PMID 31232177›Full record

ArticleAutophagy2020

Circular RNA

Xiuyuan Chen, Rui Mao, Wenmei Su, Xia Yang, Qianqian Geng, Chunfang Guo, Zhuwen Wang, Jun Wang, Laura A Kresty, David G Beer and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed, 2 pooled it
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

199 citing papers in PubMed, 2 syntheses or guidelines pooled it, 346 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Cancers · 2026
    Review
  4. Review
  5. Review
  6. Insights Into circRNA-Mediated Lipid Metabolism in Cancer Progression.Journal of cellular and molecular medicine · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Exosomal CircMFN2 Enhances the Progression of Pituitary Adenoma via the MiR-146a-3p/TRAF6/NF-κB Pathway.Journal of neurological surgery. Part A, Central European neurosurgery · 2025
    Article
  19. Review
  20. Review

139 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Xiuyuan ChenDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Rui MaoCancer Center, Xinjiang Medical University, Urumqi, China.
Wenmei SuDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Xia YangThe First Affiliated Hospital, Xian Jiaotong University, Xi'an, China.
Qianqian GengThe First Affiliated Hospital, Xian Jiaotong University, Xi'an, China.
Chunfang GuoSection of Thoracic Surgery, Department of Surgery, Rogel Cancer Center, University of Michigan, Ann Arbor, USA.
Zhuwen WangSection of Thoracic Surgery, Department of Surgery, Rogel Cancer Center, University of Michigan, Ann Arbor, USA.
Jun WangDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Laura A KrestySection of Thoracic Surgery, Department of Surgery, Rogel Cancer Center, University of Michigan, Ann Arbor, USA.
David G BeerSection of Thoracic Surgery, Department of Surgery, Rogel Cancer Center, University of Michigan, Ann Arbor, USA.
Andrew C ChangSection of Thoracic Surgery, Department of Surgery, Rogel Cancer Center, University of Michigan, Ann Arbor, USA.ORCID 0000-0001-9506-0425
Guoan ChenSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.
University of Michigan · USFirst Affiliated Hospital of Xi'an Jiaotong University · CNPeking University · CNGuangdong Medical College · CNSouthern University of Science and Technology · CNXinjiang Medical University · CN

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THEODORE S LAWRENCE · 1988 to 2026
$178.2M
Squamous Cell Carcinoma of the Lung: Validation of Molecular Signatures for PrognU01CA157715 · NCI · UNIVERSITY OF COLORADO DENVER · PI HIRSCH, FRED R · 2012 to 2016
$2.9M
Identification and Characterization of Gene Fusions in Lung AdenocarcinomaR01CA154365 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BEER, DAVID GEORGE, CHINNAIYAN, ARUL M · 2011 to 2015
$1.4M
Validation of 4-miRNA signature for early lung cancer detectionR21CA205414 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHEN, GUOAN · 2016 to 2017
$382k
NCI NIH HHS P30 CA046592NCI NIH HHS R01 CA154365NCI NIH HHS R21 CA205414NCI NIH HHS U01 CA157715
6 · The paper itself

Abstract

The role of circular RNA in cancer is emerging. A newly reported circular RNA

Indexed as

Signal TransductionAMP-Activated Protein Kinase KinasesAMP-Activated Protein KinasesAutophagyCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsMicroRNAsProtein Serine-Threonine KinasesRNA, CircularSTAT3 Transcription FactorAMP-Activated Protein Kinase KinasesAMP-Activated Protein KinasesMicroRNAsMIRN124 microRNA, humanProtein Serine-Threonine KinasesRNA, CircularSTAT3 protein, humanSTAT3 Transcription FactorSTK11 protein, humanCell deathceRNAcircRNAHIPK3prognosisSTK11

Identifiers

PMID31232177
PMCPMC7138221
OpenAlexW2953225943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.