ArticleMagnetic resonance in medicine2019
Robust pCASL perfusion imaging using a 3D Cartesian acquisition with spiral profile reordering (CASPR).
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 19 citations in OpenAlex.
- Recent advances in arterial spin labeling MRI for imaging brain tumors.Magma (New York, N.Y.) · 2026Review
- Next Generation 7 Tesla Arterial Spin Labeling With Rotated Spiral Acquisition Enables Mesoscale Resolution in 3D Brain Perfusion and Functional MRI.Magnetic resonance in medicine · 2026Article
- A straightforward approach for 3D single-shot arterial spin labeling-based brain perfusion imaging: Preventing artifacts due to signal fluctuations.Magnetic resonance in medicine · 2025Article
- Repeatability and Reproducibility of Pseudocontinuous Arterial Spin-Labeling-Measured Brain Perfusion in Healthy Volunteers and Patients with Glioblastoma.AJNR. American journal of neuroradiology · 2025Article
- Quantitative non-contrast perfusion MRI in the body using arterial spin labeling.Magma (New York, N.Y.) · 2024Review
- Cervical spinal cord angiography and vessel-selective perfusion imaging in the rat.NMR in biomedicine · 2024Article
- Synthesizing Contrast-Enhanced MR Images from Noncontrast MR Images Using Deep Learning.AJNR. American journal of neuroradiology · 2024Article
- Longitudinal assessment of placental perfusion in normal and hypertensive pregnancies using pseudo-continuous arterial spin-labeled MRI: preliminary experience.European radiology · 2023Article
- Arterial spin labeling using spatio-temporal encoding readout for robust perfusion imaging in inhomogenous magnetic fields.Magnetic resonance in medicine · 2023Article
- Recent Technical Developments in ASL: A Review of the State of the Art.Magnetic resonance in medicine · 2022Review
- HyperpolarizedMagnetic resonance in medicine · 2022Review
- Intrasession Reliability of Arterial Spin-Labeled MRI-Measured Noncontrast Perfusion in Glioblastoma at 3 T.Tomography (Ann Arbor, Mich.) · 2020Article
- Consensus-based technical recommendations for clinical translation of renal ASL MRI.Magma (New York, N.Y.) · 2020Article
- Robust pCASL perfusion imaging using a 3D Cartesian acquisition with spiral profile reordering (CASPR).Magnetic resonance in medicine · 2019Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo improve the robustness of arterial spin-labeled measured perfusion using a novel Cartesian acquisition with spiral profile reordering (CASPR) 3D turbo spin echo (TSE) in the brain and kidneys.
methodsThe CASPR view ordering followed a pseudo-spiral trajectory on a Cartesian grid, by sampling the center of k-space at the beginning of each echo train of a segmented 3D TSE acquisition. With institutional review board approval and written informed consent, 14 normal subjects (9 brain and 5 kidneys) were scanned with pCASL perfusion imaging using 3D CASPR and compared against 3D linear TSE (brain and kidneys), the established 2D EPI and 3D gradient and spin echo perfusion (brain), and 2D single-shot turbo spin-echo perfusion (kidneys). The SNR and the quantitative perfusion values were compared among different acquisitions.
results3D CASPR TSE achieved robust perfusion across all slices compared to 3D linear TSE in the brain and kidneys. Compared to 2D EPI, 3D CASPR TSE showed higher SNR across the brain (P < 0.01), and exhibited good agreement (36.4 ± 4.7 and 36.9 ± 5.3 mL/100 g/min with 2D EPI and 3D CASPR, respectively), and with 3D gradient and spin echo (27.9 ± 7.2 mL/100 g/min). Compared to a single slice 2D single-shot turbo spin-echo acquisition, 3D CASPR TSE achieved robust perfusion across the entire kidneys in similar scan time with comparable quantified perfusion values (154.1 ± 74.6 and 151.7 ± 70.6 mL/100 g/min with 2D single-shot turbo spin-echo and 3D CASPR, respectively).
conclusionThe CASPR view ordering with 3D TSE achieves robust arterial spin-labeled perfusion in the brain and kidneys because of the sampling of the center of k-space at the beginning of each echo train.
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