ArticleCurrent opinion in physiology2018
Sex differences in the response to dietary restriction in rodents.
Article in Current opinion in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Epigenome-wide Association Study Analysis of Calorie Restriction in Humans, CALERIETM Trial Analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Trial
- Trial
- Effect of 2 years of calorie restriction on liver biomarkers: results from the CALERIE phase 2 randomized controlled trial.European journal of nutrition · 2021Trial
- Time-restricted feeding extends healthspan in both sexes and lifespan in male C57BL/6 J mice.Nature aging · 2026Article
- Caloric restriction reprograms skeletal muscle molecular pathways in non-human primates: potential relevance to human aging biology.Skeletal muscle · 2026Article
- Quantitative and morphological analyses reveal microglia-specific neuroinflammation in brain regions linked to cognitive function in ovariectomized and chronic intermittent hypoxia-exposed female rats.Brain, behavior, & immunity - health · 2026Article
- Caloric Restriction and Dietary Taurine Regulate Taurine Homeostasis Through Distinct Tissue-Specific Mechanisms in Mice.Molecular nutrition & food research · 2026Article
- Sex-specific vulnerabilities in early human neurodevelopment following SARS-CoV-2-induced maternal immune activation.European child & adolescent psychiatry · 2026Article
- Sex-specific effects of automated feeding on lifespan and reproduction inFrontiers in aging · 2026Article
- Long-Term Dietary Restriction Has a Strong and Positive Effect on Both Hepatic and Peripheral Insulin Sensitivity, in an Age- and Diet-Dependent Manner.Aging cell · 2025Article
- Time-Restricted Feeding Extends Healthspan in Female and Lifespan in Male C57BL/6J Mice.bioRxiv : the preprint server for biology · 2025Article
- Article
- Surviving on Limited Resources: Effects of Caloric Restriction on Growth, Gene Expression and Gut Microbiota in a Species With Male Pregnancy (Hippocampus erectus).Molecular ecology · 2025Article
- Article
- Sexual Dimorphism in Cardiometabolic Diseases: From Development to Senescence and Therapeutic Approaches.Cells · 2025Review
- Ginkgolide B increases healthspan and lifespan of female mice.Nature aging · 2025Article
- Article
- Article
- Methionine as a regulator of bone remodeling with fasting.JCI insight · 2024Article
- Sex-Dependent Metabolic Effects in Diet-Induced Obese Rats following Intermittent Fasting Compared with Continuous Food Restriction.Nutrients · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Dietary restriction (DR) remains the most reproducible and consistent laboratory intervention to extend lifespan and improve health in mammals. DR has been primarily characterized in males due to issues of cost, perceived heightened variability amongst females, and the misconception that the reproductive system is the only important difference between sexes in mammals. In reality, existing data point to clear sex differences in mammalian responses to DR. Here we discuss recent advances in our understanding of sex differences in the responses to DR in rodent models.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.