Evidence map›Paper›PMID 31231693›Full record

ArticleCommunications biology2019

TRAV1-2

Emily B Wong, Marielle C Gold, Erin W Meermeier, Bongiwe Z Xulu, Sharon Khuzwayo, Zuri A Sullivan, Eisa Mahyari, Zoe Rogers, Hénrik Kløverpris, Prabhat K Sharma and 18 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
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  7. Sorting endosomes play key roles in presentation ofbioRxiv : the preprint server for biology · 2025
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  18. Review
  19. Role of MHC class I pathways inFrontiers in cellular and infection microbiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 15 institutions in 7 countries.

Emily B Wong *1Africa Health Research Institute, KwaZulu-Natal, South Africa.ORCID 0000-0003-4755-5380
Marielle C Gold *5Department of Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, OR USA.ORCID 0000-0003-2505-3291
Erin W Meermeier5Department of Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, OR USA.ORCID 0000-0002-9709-7624
Bongiwe Z Xulu1Africa Health Research Institute, KwaZulu-Natal, South Africa.
Sharon Khuzwayo1Africa Health Research Institute, KwaZulu-Natal, South Africa.ORCID 0000-0003-4482-5955
Zuri A Sullivan1Africa Health Research Institute, KwaZulu-Natal, South Africa.ORCID 0000-0002-6111-6512
Eisa Mahyari8Division of Bioinformatics and Computational Biology (BCB), Department of Medical Informatics and Clinical Epidemiology (DMICE), Oregon Health & Science University, Portland, OR USA.
Zoe Rogers1Africa Health Research Institute, KwaZulu-Natal, South Africa.
Hénrik Kløverpris1Africa Health Research Institute, KwaZulu-Natal, South Africa.
Prabhat K Sharma6VA Portland Health Care System, Portland, OR USA.
Aneta H Worley6VA Portland Health Care System, Portland, OR USA.
Umesh Lalloo10Durban University of Technology, Durban, South Africa.
Prinita Baijnath10Durban University of Technology, Durban, South Africa.
Anish AmbaramDepartment of Pulmonology, Inkosi Albert Luthuli Hospital, Durban, South Africa.
Leon NaidooDepartment of Pulmonology, Inkosi Albert Luthuli Hospital, Durban, South Africa.
Moosa SulemanDepartment of Pulmonology, Inkosi Albert Luthuli Hospital, Durban, South Africa.
Rajhmun Madansein13Department of Cardiothoracic Surgery, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
James E McLaren15Institute of Infection & Immunity, Cardiff University School of Medicine, Cardiff, Wales UK.ORCID 0000-0002-7021-5934
Kristin Ladell15Institute of Infection & Immunity, Cardiff University School of Medicine, Cardiff, Wales UK.ORCID 0000-0002-9856-2938
Kelly L Miners15Institute of Infection & Immunity, Cardiff University School of Medicine, Cardiff, Wales UK.
David A Price15Institute of Infection & Immunity, Cardiff University School of Medicine, Cardiff, Wales UK.ORCID 0000-0001-9416-2737
Samuel M Behar17Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA USA.ORCID 0000-0002-3374-6699
Morten Nielsen18Center for Biological Sequence Analysis, Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark.ORCID 0000-0001-7885-4311
Victoria O Kasprowicz1Africa Health Research Institute, KwaZulu-Natal, South Africa.
Alasdair Leslie1Africa Health Research Institute, KwaZulu-Natal, South Africa.
William R Bishai22Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD USA.
Thumbi Ndung'u1Africa Health Research Institute, KwaZulu-Natal, South Africa.
David M Lewinsohn5Department of Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, OR USA.ORCID 0000-0001-9906-9494
Africa Health Research Institute · ZAOregon Health & Science University · USInstitute of Infection and Immunity · CADurban University of Technology · ZAVA Portland Health Care System · USBoston Medical Center · USCentre for the AIDS Programme of Research in South Africa · ZAHarvard University · USJohns Hopkins University · USMax Planck Institute for Infection Biology · DENational Institute of Allergy and Infectious Diseases · USNational University of General San Martín · ARUniversity of Copenhagen · DKUniversity of KwaZulu-Natal · ZAUniversity of Massachusetts Chan Medical School · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Multidisciplinary HIV Training ProgramT32AI007387 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Daniel R. Kuritzkes · 1990 to 2026
$8.8M
Mycobacterium tuberculosis Survival Regulatory GenesR01AI037856 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BISHAI, WILLIAM RAMSES · 1997 to 2020
$7.2M
Regulation of CD8+ T cell immunity to tuberculosis (pending title)R01AI106725 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BEHAR, SAMUEL M · 2013 to 2022
$6.1M
Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3M
Recognition of Mtb-infected Cells by CD8+ T LymphocytesR01AI048090 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M. · 2001 to 2016
$4.2M
Lung Resident, MR1-Restricted T Cells: Association with Differential Outcomes Following Exposure to M. TuberculosisR01AI134790 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., WALZL, GERHARD · 2018 to 2022
$3.3M
Biomarkers and Signaling in TuberculosisR01AI097138 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BISHAI, WILLIAM RAMSES · 2011 to 2014
$2.4M
Memory, Phenotype, and Function of TB-reactive Human MR1 Restricted T cellsR01AI129980 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., LEWINSOHN, DEBORAH A. · 2019 to 2022
$2.4M
Mechanisms of recognition by Mycobacterium tuberculosis-reactive thymocytesR01AI078965 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI GOLD, MARIELLE C. · 2010 to 2013
$1.1M
Studies of Mucosal Associated Invariant T (MAIT) cells in people with HIV, TB and HIV/TB co-infection in South AfricaK08AI118538 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WONG, EMILY BETH · 2015 to 2019
$950k
Recognition of Mtb-Infected Cells by Non-Classically Restritcted CD8+ T CellsI01BX000533 · VA · PORTLAND VA MEDICAL CENTER · PI LEWINSOHN, DAVID M. · 2011 to 2024
–
BLRD VA I01 BX000533BLRD VA I01 BX001231NHLBI NIH HHS T32 HL083808NIAID NIH HHS K08 AI118538NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI037856NIAID NIH HHS R01 AI048090NIAID NIH HHS R01 AI078965NIAID NIH HHS R01 AI097138NIAID NIH HHS R01 AI106725NIAID NIH HHS R01 AI129980NIAID NIH HHS R01 AI134790NIAID NIH HHS T32 AI007387Wellcome TrustWellcome Trust 107752/Z/15/Z
6 · The paper itself

Abstract

Mucosal-associated invariant T (MAIT) cells typically express a TRAV1-2

Indexed as

AnimalsBronchiBronchoalveolar Lavage FluidBronchoscopyCD8-Positive T-LymphocytesHistocompatibility Antigens Class IHumansImmune SystemInflammationIntestinesLungMiceMinor Histocompatibility AntigensMucosal-Associated Invariant T CellsMycobacterium tuberculosisOregonHistocompatibility Antigens Class IMinor Histocompatibility AntigensReceptors, Antigen, T-Cell, alpha-betaMucosal immunologyT-cell receptorTuberculosis

Identifiers

PMID31231693
PMCPMC6549148
OpenAlexW2948089261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.