Evidence map›Paper›PMID 31231691›Full record

ArticleWellcome open research2019

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive

Edna M Ondari, Elizabeth J Klemm, Chisomo L Msefula, Moataz Abd El Ghany, Jennifer N Heath, Derek J Pickard, Lars Barquist, Gordon Dougan, Robert A Kingsley, Calman A MacLennan

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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  3. AfricanmBio · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 7 countries.

Edna M OndariSwiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0002-4073-2973
Elizabeth J KlemmWellcome Trust Sanger Institute, Hinxton, UK.
Chisomo L MsefulaWellcome Trust Sanger Institute, Hinxton, UK.ORCID https://orcid.org/0000-0003-2304-886X
Moataz Abd El GhanyWellcome Trust Sanger Institute, Hinxton, UK.
Jennifer N HeathInstitute of Immunology and Immuotherapy, University of Birmingham, Birmingham, UK.
Derek J PickardWellcome Trust Sanger Institute, Hinxton, UK.
Lars BarquistWellcome Trust Sanger Institute, Hinxton, UK.ORCID https://orcid.org/0000-0003-4732-2667
Gordon DouganWellcome Trust Sanger Institute, Hinxton, UK.
Robert A Kingsley *Quadram Institute Bioscience, Norwich, UK.
Calman A MacLennan *Institute of Immunology and Immuotherapy, University of Birmingham, Birmingham, UK.
Wellcome Sanger Institute · GBQuadram Institute · GBSwiss Tropical and Public Health Institute · CHThe University of Sydney · AUUniversity of Birmingham · GBUniversity of Cambridge · GBUniversity of Liverpool · GBUniversity of Oxford · GBUniversity of Würzburg · DE

Funding

Medical Research Council MR/P008852/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibodycomplementgenomeInvasive salmonellosisserum resistancetranscriptome

Identifiers

PMID31231691
PMCPMC6560496
OpenAlexW2941868751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.