ReviewNPJ microgravity2019
Supplying a pharmacy for NASA exploration spaceflight: challenges and current understanding.
Review in NPJ microgravity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Spaceflight-guided pharmacogenomics: a foundational analysis of pharmaceuticals and their responsive gene targets in the space environment.Frontiers in physiology · 2026Pooled it
- [Mechanisms and protective strategies for astronaut skin injury in deep space environments].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Pooled it
- Crystallization for Manufacturing in Microgravity; Are We There Yet?Crystal growth & design · 2026Article
- Beyond Earth: Recent Advancements in Microgravity Biomedical and Genetic Research in Saudi Arabia.International journal of molecular sciences · 2026Review
- Review of carbon dioxide removal and recycling in space.NPJ microgravity · 2026Review
- Pilot degradation study of gamma irradiated ciprofloxacin in its primary packaging material for space pharmaceutical applications.Scientific reports · 2026Article
- Emerging Chemical and Biological Materials Technologies in the Extraplanetary Environment.Nano-micro letters · 2026Review
- Streamlined molecular farming of plant virus therapeutics for space flight and other low-resource environments.NPJ science of plants · 2026Article
- Quantum engineered MXene-graphene-plasmonic nanocomposites for next-generation transparent and flexible space photovoltaics.Turkish journal of chemistry · 2026Article
- Spaceflight and Medical Microbiology: Possible Implications for Standard Infection Diagnostics and Therapy.Life (Basel, Switzerland) · 2025Article
- Pharmaceutical and biomedical challenges for crew autonomy in health preservation during future exploration missions.Communications medicine · 2025Review
- Deep space environment empowering drug design and development.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- Congestion and Sinonasal Illness in Outer Space: A Study on the International Space Station.Laryngoscope investigative otolaryngology · 2025Article
- How to keep astronauts healthy in deep space.Nature · 2025Article
- Management of corneal injuries in spaceflight and recommendations for planetary missions.NPJ microgravity · 2025Article
- Repetitive stability study of remdesivir/cyclodextrin complex on the international space station.Scientific reports · 2025Article
- Acetaminophen production in the edible, filamentous cyanobacterium Arthrospira platensis.Biotechnology and bioengineering · 2025Article
- taVNS as a potential countermeasure for neurocognitive decline in microgravity.Frontiers in neuroscience · 2025Article
- Space exploration and lifestyle medicine: a narrative review of its implications for astronaut health and remote Earth-based environments.Frontiers in physiology · 2025Review
- On the nose: nasal neurostimulation as a technology countermeasure for sinonasal congestion in astronauts.Frontiers in physiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to maintain crew health and performance during long-duration spaceflight outside of low-Earth orbit, NASA and its international partners must be capable of providing a safe and effective pharmacy. Given few directed studies of pharmaceuticals in the space environment, it is difficult to characterize pharmaceutical effectiveness or stability during spaceflight; this in turn makes it challenging to select an appropriate formulary for exploration. Here, we present the current state of literature regarding pharmaceutical stability, metabolism, and effectiveness during spaceflight. In particular, we have attempted to highlight the gaps in current knowledge and the difficulties in translating terrestrial-based drug studies to a meaningful interpretation of drug stability, safety, and effectiveness in space. We hope to identify high-yield opportunities for future research that might better define and mitigate pharmaceutical risk for exploration missions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.