Evidence map›Paper›PMID 31231621›Full record

SynthesisFrontiers in pediatrics2019

Prescribing Controversies: An Updated Review and Meta-Analysis on Combined/Alternating Use of Ibuprofen and Paracetamol in Febrile Children.

Giulia Trippella, Martina Ciarcià, Maurizio de Martino, Elena Chiappini

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Observational
  4. Review
  5. Review
  6. Review
  7. Effect of ibuprofen on amelogenesis in Wistar rats.Journal of applied oral science : revista FOB · 2025
    Article
  8. Article
  9. The Three W's of Acetaminophen In Children: Who, Why, and Which Administration Mode.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Understanding Discomfort in Order to Appropriately Treat Fever.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Giulia TrippellaDepartment of Health Sciences, Post-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, University of Florence, Florence, Italy.
Martina CiarciàDepartment of Health Sciences, Post-Graduate School of Pediatrics, Anna Meyer Children's University Hospital, University of Florence, Florence, Italy.
Maurizio de MartinoDepartment of Health Sciences, University of Florence, Florence, Italy.
Elena ChiappiniDivision of Pediatric Infectious Disease, Department of Health Sciences, Anna Meyer Children's University Hospital, University of Florence, Florence, Italy.
Meyer Children's Hospital · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acetaminophenantipyreticschildrenfeveribuprofenparacetamol

Identifiers

PMID31231621
PMCPMC6560148
OpenAlexW2966957983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.