ArticleFrontiers in microbiology2019
A Real-Time Multiplexed Microbial Growth Intervalometer for Capturing High-Resolution Growth Curves.
Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Cultivating efficiency: high-throughput growth analysis of anaerobic bacteria in compact microplate readers.Microbiology spectrum · 2024Article
- Cultivating efficiency: High-throughput growth analysis of anaerobic bacteria in compact microplate readers.bioRxiv : the preprint server for biology · 2023Article
- Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
Batch cultures are a low maintenance and routine culturing method in microbiology. Automated tools that measure growth curves from microorganisms grown in traditional laboratory glassware, such as Balch-type tubes, are not commercially available. Here, we present a new MicrobiAl Growth Intervalometer (MAGI) that measures optical density as it correlates to microbial growth by utilizing photo-conduction as opposed to photo-attenuation used by traditional OD measurement equipment. Photo-attenuation occurs when biomass in suspension within a medium blocks and/or diffuses light directed at the detector, such that an increase in biomass results in a decrease in the measured signal. Photo-conduction differs in which the biomass contained in a medium conducts light from the emitter to the detector, where an increase in the biomass results in a corresponding increase in the measured signal. MAGI features software-driven automation that provides investigators with a highly sensitive, low-background noise growth measurement instrument with added capabilities for remote visualization and data acquisition. It is a low maintenance, cost effective, versatile, and robust platform for aerobic/anaerobic cultivation. We demonstrate the versatility of this device by obtaining growth curves from two common laboratory organisms
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