ReviewFrontiers in endocrinology2019
Nutrition and Female Fertility: An Interdependent Correlation.
Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 200 citations in OpenAlex.
- The influence of lifestyle interventions and overweight on infertility: a systematic review, meta-analysis, and meta-regression of randomized controlled trials.Frontiers in medicine · 2023Pooled it
- Dietary Modification for Reproductive Health in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Potential Role of Prebiotics and Probiotics on Oocyte Quality, Embryo Development, Endometrial Health, and Fertility Outcomes in Assisted Reproductive Technologies.Probiotics and antimicrobial proteins · 2026Review
- Research progress on multi-mechanism analysis and protection strategies of ovarian aging and fertility decline.Journal of ovarian research · 2026Review
- Birth Weight in the Daasanach Community of Northern Kenya and the Effect of Multiparity.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- Nutritional Regulation of Ovarian Bioenergetics: Implications for Reproductive Aging and Female Infertility.Nutrients · 2026Review
- Hydroxytyrosol Enhances the Nrf2/HO-1 Signalling Pathway to Inhibit Oxidative Stress and Apoptosis and Improve Premature Ovarian Insufficiency In Vitro and In Vivo.International journal of molecular sciences · 2026Article
- Precipitation variability, fertility, and metabolic stress over 5 millennia in the ancient Andes: A bioarchaeological path analysis.Science advances · 2026Article
- Dietary diversity among reproductive aged women attending urban and rural healthcare facilities, Middle Delta, Egypt.BMC public health · 2026Article
- A multicountry, multicenter report to identify nutritional risks in female populations using the FIGO Nutrition Checklist.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Association between the serum uric acid-to-HDL-cholesterol ratio and female infertility: The mediating role of BMI.Medicine · 2026Article
- Identification of Dietary Patterns Among Women Undergoing Assisted Reproduction and Its Association with Reproductive Outcomes.International journal of women's health · 2026Article
- The Role of Diet in Women of Childbearing Age: Current Evidence Supporting Nutritional Recommendations.Nutrients · 2025Review
- From gut to gamete: how the microbiome influences fertility and preconception health.Microbiome · 2025Review
- Factors Associated with Fruit and Vegetable Intake Among Women of Reproductive Age in Flint, Michigan: A Cross-Sectional Analysis.Healthcare (Basel, Switzerland) · 2025Article
- Examining the Relationship Between Dietary Glycemic Load (GL), Glycemic Index (GI), and the Odds of Diminished Ovarian Reserve: A Case-Control Study.Food science & nutrition · 2025Article
- Relationships between inflammatory indicators, nutritional status, and metabolic status and female infertility.Reproductive health · 2025Article
- Lifestyle factors and health outcomes associated with infertility in women: A case-control study using National Health Insurance Database.Reproductive health · 2025Article
- Evaluation of the MyFertiCoach Lifestyle App for Subfertile Couples: Single-Center Evaluation of Augmented Standard Care.JMIR formative research · 2025Observational
- A disturbed communication between hypothalamic-pituitary-ovary axis and gut microbiota in female infertility: is diet to blame?Journal of translational medicine · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Besides aging, a number of non-modifiable lifestyle-related factors, such as smoking, elevated consumption of caffeine and alcohol, stress, agonist sports, chronic exposure to environmental pollutants, and other nutritional habits exert a negative impact on a women's fertility. In particular, metabolic disorders including diabetes, obesity, and hyperlipidemia commonly associated to hypercaloric diets are suspected to affect a woman's fertility either by direct damage to oocyte health and differentiation, or by indirect interference with the pituitary-hypothalamic axis, resulting in dysfunctional oogenesis. Obese women show decreased insulin sensitivity determining persistent hyperinsulinemia, which may be involved in the pathogenesis of Polycystic Ovary Syndrome. Thus, the reduced insulin secretion induced by dietary adjustments is an attractive non-pharmacological treatment to prevent infertility, and a Mediterranean diet aimed at maintaining normal body mass may be effective in the preservation of ovarian health and physiology. Furthermore, in relation to the oxidative stress as a co-factor of defective oocyte maturation, an appropriate intake of proteins, antioxidants and methyl-donor supplements (1-Carbon Cycle) may decrease the bioavailability of toxic oxidants resulting in the protection of oocyte maturation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.