ArticleFrontiers in cellular neuroscience2019
Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.
Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 32 citations in OpenAlex.
- Transcriptomic analysis of spinal V1 interneurons informs their multifunctional role in motor output.Nature communications · 2026Article
- A transient sex-biased transcriptional program shapes early postnatal L2/3 neuron development.Biology of sex differences · 2026Article
- Evidence for chronological diversification of spinal neuron subtypes by a shared sequence of transcription factors.Science advances · 2026Article
- Neurotrophin-3 produced by motor neurons non-cell autonomously regulate the development of pre-motor interneurons in the developing spinal cord.bioRxiv : the preprint server for biology · 2026Article
- Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner.Genome biology · 2025Article
- Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3.Nature communications · 2024Article
- Lhx4 surpasses its paralog Lhx3 in promoting the differentiation of spinal V2a interneurons.Cellular and molecular life sciences : CMLS · 2024Article
- Arid3c identifies an uncharacterized subpopulation of V2 interneurons during embryonic spinal cord development.Frontiers in cellular neuroscience · 2024Article
- Potential contribution of spinal interneurons to the etiopathogenesis of amyotrophic lateral sclerosis.Frontiers in neuroscience · 2024Review
- Brain-wide mapping of efferent projections of glutamatergic (Onecut3Acta physiologica (Oxford, England) · 2023Article
- CUT homeobox genes: transcriptional regulation of neuronal specification and beyond.Frontiers in cellular neuroscience · 2023Review
- Transcription Factors as Important Regulators of Changes in Behavior through Domestication of Gray Rats: Quantitative Data from RNA Sequencing.International journal of molecular sciences · 2022Article
- Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease.Biomedicines · 2022Article
- A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys.Nature communications · 2022Article
- The Prevailing Role of Topoisomerase 2 Beta and its Associated Genes in Neurons.Molecular neurobiology · 2021Review
- A shared transcriptional code orchestrates temporal patterning of the central nervous system.PLoS biology · 2021Article
- The Temporal Mechanisms Guiding Interneuron Differentiation in the Spinal Cord.International journal of molecular sciences · 2021Review
- Article
- Impact of Reck expression and promoter activity in neuronal in vitro differentiation.Molecular biology reports · 2021Article
- Onecut Regulates Core Components of the Molecular Machinery for Neurotransmission in Photoreceptor Differentiation.Frontiers in cell and developmental biology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acquisition of proper neuronal identity and position is critical for the formation of neural circuits. In the embryonic spinal cord, cardinal populations of interneurons diversify into specialized subsets and migrate to defined locations within the spinal parenchyma. However, the factors that control interneuron diversification and migration remain poorly characterized. Here, we show that the Onecut transcription factors are necessary for proper diversification and distribution of the V2 interneurons in the developing spinal cord. Furthermore, we uncover that these proteins restrict and moderate the expression of spinal isoforms of
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