ArticleNeuron2019
Transforming the Choice Outcome to an Action Plan in Monkey Lateral Prefrontal Cortex: A Neural Circuit Model.
Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Article
- A neural circuit framework for economic choice: from building blocks of valuation to compositionality in multitasking.bioRxiv : the preprint server for biology · 2025Article
- Semi-orthogonal subspaces for value mediate a binding and generalization trade-off.Nature neuroscience · 2024Article
- Semi-orthogonal subspaces for value mediate a tradeoff between binding and generalization.ArXiv · 2023Article
- Value dynamics affect choice preparation during decision-making.Nature neuroscience · 2023Article
- The orbitofrontal cortex: A goal-directed cognitive map framework for social and non-social behaviors.Neurobiology of learning and memory · 2023Review
- Article
- Taking stock of value in the orbitofrontal cortex.Nature reviews. Neuroscience · 2022Review
- A structural and functional subdivision in central orbitofrontal cortex.Nature communications · 2022Article
- Neuronal origins of reduced accuracy and biases in economic choices under sequential offers.eLife · 2022Article
- Category learning in a recurrent neural network with reinforcement learning.Frontiers in psychiatry · 2022Article
- Social processing by the primate medial frontal cortex.International review of neurobiology · 2021Review
- Signal dynamics of midbrain dopamine neurons during economic decision-making in monkeys.Science advances · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
In economic decisions, we make a good-based choice first, then we transform the outcome into an action to obtain the good. To elucidate the network mechanisms for such transformation, we constructed a neural circuit model consisting of modules representing choice, integration of choice with target locations, and the final action plan. We examined three scenarios regarding how the final action plan could emerge in the neural circuit and compared their implications with experimental data. Our model with heterogeneous connectivity predicts the coexistence of three types of neurons with distinct functions, confirmed by analyzing the neural activity in the lateral prefrontal cortex (LPFC) of behaving monkeys. We obtained a much more distinct classification of functional neuron types in the ventral than the dorsal region of LPFC, suggesting that the action plan is initially generated in ventral LPFC. Our model offers a biologically plausible neural circuit architecture that implements good-to-action transformation during economic choice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.