Evidence map›Paper›PMID 31230730›Full record

ReviewClinics in geriatric medicine2019

Aging and Hematopoiesis.

Emma M Groarke, Neal S Young

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinics in geriatric medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Biomolecular Basis of Life.Metabolites · 2025
    Review
  10. Article
  11. The Sympathetic Nervous Influence on Hematopoiesis Up To Date.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Erythropoietin levels in geriatric anemia.Journal of family medicine and primary care · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emma M GroarkeHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Mark Hatfield Clinical Research Center, Room 3E-5140, 10 Center Drive, Bethesda, MD 20891-1202, USA. Electronic address: emma.groarke@nih.gov.
Neal S YoungHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Mark Hatfield Clinical Research Center, Room 3E-5140, 10 Center Drive, Bethesda, MD 20891-1202, USA.

Funding

Pathogenesis And Treatment Of Aplastic AnemiaZIAHL002315 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI YOUNG, NEAL S · 2009 to 2025
$60.1M
Intramural NIH HHS Z99 HL999999
6 · The paper itself

Abstract

In hematopoiesis, mature blood cells, granulocytes, erythrocytes, and megakaryocytes originate from hematopoietic stem cells. With age, changes in hematopoiesis may have clinical consequences: defective immune responses, cytopenias (most commonly anemia and lymphopenia), hematological malignancy, and effects mediated by hematopoietic cells in other organs. Clonal hematopoiesis is commonly seen with aging and has been associated with both blood concerns and atherosclerosis, but further study is required to determine a causative link.

Indexed as

AgedAgingAnemiaFemaleHematopoiesisHumansMaleAnemia in the elderlyClonal cytopenia of undetermined significanceClonal hematopoiesis of indeterminate potentialHematopoiesis

Identifiers

PMID31230730
PMCPMC8131033

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.