SynthesisInternational wound journal2019
A comparison of flap reconstruction vs the laying open technique or excision and direct suture for pilonidal sinus disease: A meta-analysis of randomised studies.
Synthesis in International wound journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Laser treatment of pilonidal disease: a systematic review.Lasers in medical science · 2022Pooled it
- A mapping review of sacrococcygeal pilonidal sinus disease.Techniques in coloproctology · 2021Pooled it
- A comparison of flap reconstruction vs the laying open technique or excision and direct suture for pilonidal sinus disease: A meta-analysis of randomised studies.International wound journal · 2019Pooled it
- Is it beneficial to add laser ablation to curettage in the treatment of pilonidal sinus disease?Lasers in medical science · 2025Trial
- Excision and suture in the midline versus Karydakis flap surgery for pilonidal sinus: randomized clinical trial.BJS open · 2022Trial
- Probe-Guided Core Excision for Complete Sinus Tract Removal in Pilonidal Disease.Annals of dermatology · 2026Article
- Open Pilonidal Excision as a Translational Human Model for Wound Healing and Skin Regeneration Research.Biomedicines · 2026Review
- Association between pilonidal sinus disease and depression: a population-based cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Combined laser ablation and pit excision for pilonidal sinus: effectiveness, quality of recovery, and patient-reported outcomes.BMC surgery · 2025Article
- Future of pilonidal cyst surgery: a comparative review of traditional and laser techniques.BMC surgery · 2025Review
- Comparative Outcomes of Surgical Techniques for Pilonidal Sinus: A Turkish Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Efficacy of laser obliteration with limited excision of pilonidal sinus.The Journal of international medical research · 2024Observational
- Comparison of laser ablation, simple excision, and flap reconstruction in the treatment of pilonidal sinus disease.Lasers in medical science · 2024Article
- Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of pilonidal disease.Techniques in coloproctology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many treatments have been described for pilonidal disease, but recurrence cannot be completely eliminated. The aim of this study was to perform a meta-analysis of randomised, controlled trials comparing flap repair vs the laying open technique and/or excision and direct closure techniques in the treatment of chronic pilonidal sinus disease. The primary outcome measure was the recurrence rate. Secondary outcomes were complete wound-healing time, duration of the incapacity to work, quality of life and patient satisfaction, postoperative pain, wound infection, bleeding or haematoma, skin wound complications, and duration of hospital stay. Seventeen studies were included. The meta-analysis demonstrated a lower risk of recurrence, a shorter duration of incapacity to work, a lower risk of wound infections, a lower risk of skin wound complications, and a shorter duration of hospitalisation in favour of flap vs direct closure. A shorter time to complete wound healing and a shorter duration of incapacity to work for flap vs the laying open technique were observed. Superiority of flap repair vs direct closure in pilonidal sinus treatment was demonstrated in this meta-analysis. These results suggest avoiding primary direct closure in clinical practice. Compared with the laying open technique, flaps result in faster healing and a shorter time to return to activities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.