Evidence map›Paper›PMID 31230144›Full record

ArticlePsychopharmacology2019

Modeling subjective belief states in computational psychiatry: interoceptive inference as a candidate framework.

Xiaosi Gu, Thomas H B FitzGerald, Karl J Friston

Abstract read
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Body as First Teacher: The Role of Rhythmic Visceral Dynamics in Early Cognitive Development.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Computational Psychiatry Needs Time and Context.Annual review of psychology · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaosi GuDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, Box 1230, New York, NY, 10029, USA. xiaosi.gu@mssm.edu.ORCID http://orcid.org/0000-0002-9373-987X
Thomas H B FitzGeraldSchool of Psychology, University of East Anglia, Norwich Research Park, Norwich, Norfolk, NR4 7TJ, UK.
Karl J FristonWellcome Centre for Human Neuroimaging, University College London, London, England.

Funding

Computational and Neural Modeling of Cue Reactivity in AddictionR01DA043695 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI · 2018 to 2022
$2.9M
Transforming Genomics with 5 PB Big Omics Data Engine Cray CS300-AC SupercomputerS10OD018522 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2014 to 2014
$1.9M
NIDA NIH HHS R01 DA043695NIH HHS S10 OD018522
6 · The paper itself

Abstract

The nascent field computational psychiatry has undergone exponential growth since its inception. To date, much of the published work has focused on choice behaviors, which are primarily modeled within a reinforcement learning framework. While this initial normative effort represents a milestone in psychiatry research, the reality is that many psychiatric disorders are defined by disturbances in subjective states (e.g., depression, anxiety) and associated beliefs (e.g., dysmorphophobia, paranoid ideation), which are not considered in normative models. In this paper, we present interoceptive inference as a candidate framework for modeling subjective-and associated belief-states in computational psychiatry. We first introduce the notion and significance of modeling subjective states in computational psychiatry. Next, we present the interoceptive inference framework, and in particular focus on the relationship between interoceptive inference (i.e., belief updating) and emotions. Lastly, we will use drug craving as an example of subjective states to demonstrate the feasibility of using interoceptive inference to model the psychopathology of subjective states.

Indexed as

Computer SimulationCultureDiagnostic Self EvaluationModels, PsychologicalChoice BehaviorCravingEmotionsFemaleHumansLearningMaleMental DisordersPsychiatryComputational psychiatryCravingEmotionInteroceptive inferenceSubjective beliefs states

Identifiers

PMID31230144
PMCPMC6697568

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.