Evidence map›Paper›PMID 31230017›Full record

ArticleBMJ open2019

Intermittent preventive treatment of pregnant women in Kintampo area of Ghana with sulphadoxine-pyrimethamine (SP): trends spanning 2011 and 2015.

Felix Boakye Oppong, Stephaney Gyaase, Charles Zandoh, Obed Ernest A Nettey, Seeba Amenga-Etego, Edward Apraku Anane, Robert Adda, David Kwame Dosoo, Seth Owusu-Agyei, Kwaku Poku Asante

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Felix Boakye OppongKintampo Health Research Centre, Kintampo, Ghana.ORCID 0000-0002-3146-9958
Stephaney GyaaseKintampo Health Research Centre, Kintampo, Ghana.
Charles ZandohKintampo Health Research Centre, Kintampo, Ghana.
Obed Ernest A NetteyKintampo Health Research Centre, Kintampo, Ghana.
Seeba Amenga-EtegoKintampo Health Research Centre, Kintampo, Ghana.
Edward Apraku AnaneKintampo Health Research Centre, Kintampo, Ghana.
Robert AddaKintampo Health Research Centre, Kintampo, Ghana.
David Kwame DosooKintampo Health Research Centre, Kintampo, Ghana.
Seth Owusu-AgyeiKintampo Health Research Centre, Kintampo, Ghana.
Kwaku Poku AsanteKintampo Health Research Centre, Kintampo, Ghana.
Kintampo Health Research Centre · GHUniversity of Health and Allied Sciences · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn Ghana, intermittent preventive treatment during pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) is recommended for the prevention of malaria-related adverse outcomes. This study demonstrates the coverage of IPTp-SP use among pregnant women over a period (2011-2015) and the impact of various sociodemographic groups on the uptake of IPTp-SP.

designRetrospective analysis using data from all pregnant women in the Kintampo Health and Demographic Surveillance System area on the uptake of IPTp-SP.

settingKintampo North Municipality and Kintampo South District of Ghana.

participantsAll pregnant women in the Kintampo Health and Demographic Surveillance System area. PRIMARY AND SECONDARY OUTCOME MEASURES: The number of doses of IPTp-SP taken by pregnant women were examined. Logistic regression was used to assess the determinant of uptake of IPTp-SP while adjusting for within-subject correlation from women with multiple pregnancies.

resultsData from 2011 to 2015 with a total of 17 484 pregnant women were used. The coverage of the recommended three or more doses of IPTp-SP among all pregnant women was 40.6%, 44.0%, 45.9%, 20.9% and 32.4% in 2011, 2012, 2013, 2014 and 2015, respectively. In the adjusted analysis, age, household size, education, religion, number of antenatal care visits, ethnicity, marital status, wealth index and place of residence were significantly associated with the uptake of three or more doses of IPTp-SP. Having middle school education or higher, aged 20 years and above, visiting antenatal care five times or more (OR 2.83, 95% CI 2.64 to 3.03), being married (OR 1.10, 95% CI 1.02 to 1.19) and those in higher wealth quintiles were significantly more likely to take three or more doses of IPTp-SP.

conclusionThe uptake of the recommended three or more doses of IPTp-SP is low in the study area. We recommend a community-based approach to identify women during early pregnancy and to administer IPTp-SP.

Indexed as

AdolescentAdultAntimalarialsChildDrug Administration ScheduleDrug CombinationsEducational StatusFemaleGhanaHumansMalariaPatient Acceptance of Health CarePregnancyPregnancy Complications, ParasiticPrenatal CarePyrimethamineAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxinecoverageiptp-spkhdsskintampopregnant womensocio-demographic characteristics

Identifiers

PMID31230017
PMCPMC6596987
OpenAlexW2952554360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.