Evidence map›Paper›PMID 31228646›Full record

ReviewFungal genetics and biology : FG & B2019

Candida auris and multidrug resistance: Defining the new normal.

Shawn R Lockhart

Abstract readReview
In one paragraph

Review in Fungal genetics and biology : FG & B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A review of bloodstream infections-pathogens, pathogenesis, diagnostic strategies, treatment methods-challenges and future aspects.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Medeniyet medical journal · 2026
    Article
  6. Review
  7. Validation of molecular detection ofMicrobiology spectrum · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Journal of fungi (Basel, Switzerland) · 2026
    Review
  14. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  15. Microbiology spectrum · 2026
    Article
  16. UnderstandingJournal of medical microbiology · 2026
    Review
  17. Microbe Profile:Microbiology (Reading, England) · 2026
    Review
  18. Article
  19. Article
  20. PostoperativeInfection and drug resistance · 2026
    Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Shawn R LockhartMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: gyi2@cdc.gov.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Candida auris is an emerging species of yeast characterized by colonization of skin, persistence in the healthcare environment, and antifungal resistance. C. auris was first described in 2009 from a single isolate but has since been reported in more than 25 countries worldwide. Resistance to fluconazole and amphotericin B is common, and resistance to the echinocandins is emerging in some countries. Antifungal resistance has been shown to be acquired rather than intrinsic and the primary mechanisms of resistance to the echinocandins and azoles have been determined. There are a number of new antifungal agents in phase 2 and phase 3 clinical trials and many have activity against C. auris. This review will discuss what is currently known about antifungal resistance in C. auris, limitations to antifungal susceptibility testing, the mechanisms of resistance, and the new antifungals that are on the horizon.

Indexed as

14-alpha Demethylase InhibitorsAminopyridinesAmphotericin BAntifungal AgentsAzolesCandidaCandidiasisDrug Resistance, Multiple, FungalEchinocandinsFluconazoleHumansIsoxazolesMicrobial Sensitivity TestsPyridinesTetrazoles14-alpha Demethylase InhibitorsAminopyridinesAmphotericin BAntifungal AgentsAPX001AAzolesEchinocandinsFluconazoleIsoxazolesPyridinesTetrazolesVT-1598

Identifiers

PMID31228646
PMCPMC12012538

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.