ArticleParasitology international2019
First autochthonous case of clinical Hepatozoon felis infection in a domestic cat in Central Europe.
Article in Parasitology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Hepatozoon infections in domestic and wild Carnivora: etiology, prevalence, clinical disease, diagnosis and treatment, and redescription of Hepatozoon silvestris, H. martis, and H. ursi.Parasites & vectors · 2025Review
- Vector-borne pathogens in cats and associated fleas in southern Ethiopia.Parasites & vectors · 2025Article
- Screening Wild Birds for Tick-Borne Zoonotic Pathogens in Portugal.Pathogens (Basel, Switzerland) · 2025Article
- Hepatozoon spp. in stray cats from the metropolitan area of Rio de Janeiro, Brazil.Parasite (Paris, France) · 2024Article
- Geographical isolation and hyperendemicity ofCurrent research in parasitology & vector-borne diseases · 2024Article
- First report ofVeterinary research forum : an international quarterly journal · 2024Article
- Vector-Borne Pathogens in Stray Cats in Eastern Germany (Thuringia).Animals : an open access journal from MDPI · 2023Article
- Screening of Domestic Cats from North-Eastern Hungary forPathogens (Basel, Switzerland) · 2023Article
- Apicomplexan haemoparasites in domestic cats in Romania.Parasites & vectors · 2023Article
- Molecular survey ofFrontiers in veterinary science · 2023Article
- Molecular analysis of blood-associated pathogens in European wildcats (International journal for parasitology. Parasites and wildlife · 2022Article
- Ticks, Fleas, and Harboured Pathogens from Dogs and Cats in Cyprus.Pathogens (Basel, Switzerland) · 2022Article
- First autochthonous clinical case of Hepatozoon silvestris in a domestic cat in Italy with unusual presentation.Parasites & vectors · 2022Article
- Molecular detection ofJournal of feline medicine and surgery · 2022Article
- Molecular epidemiological study on ticks and tick-borne protozoan parasites (Apicomplexa: Cytauxzoon and Hepatozoon spp.) from wild cats (Felis silvestris), Mustelidae and red squirrels (Sciurus vulgaris) in central Europe, Hungary.Parasites & vectors · 2022Article
- Molecular Detection of Tick-Borne Agents in Cats from Southeastern and Northern Brazil.Pathogens (Basel, Switzerland) · 2022Article
- Canine and Feline Parasitology: Analogies, Differences, and Relevance for Human Health.Clinical microbiology reviews · 2021Review
- Article
- Retrospective evaluation of vector-borne pathogens in cats living in Germany (2012-2020).Parasites & vectors · 2021Article
- Arthropod-Borne Pathogens in Stray Cats from Northern Italy: A Serological and Molecular Survey.Animals : an open access journal from MDPI · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three different Hepatozoon (Apicomplexa, Hepatozoidae) species have been described infecting domestic cats in Europe (i.e. H. felis, H. canis and H. silvestris), however, reports on clinical hepatozoonosis are uncommon and treatment protocols are not clearly defined. A six-year-old male European short-hair cat from Austria presented poor general condition, lethargy, anorexia, icterus, a painful abdomen, fever, ruffled hair and a tick infestation, and it had never left Austria. Laboratory tests revealed leukopenia, thrombocytopenia and increased serum levels of symmetric dimethylarginine (SDMA) and bilirubin. In May Grünwald-Giemsa-stained blood smears, structures resembling Hepatozoon gamonts were observed inside neutrophil granulocytes. A PCR targeting a fragment of the 18S rRNA gene of Hepatozoon spp. and DNA sequencing allowed the diagnosis of H. felis-DNA in blood samples. The cat was treated with imidocarb dipropionate (6 mg/kg body weight, repeated after 14 days) and doxycycline monohydrate (5 mg/kg body weight twice a day, p.o., for four weeks) and recovered completely. A broad haematological and biochemical laboratory control after six months showed all evaluated parameters under normal ranges. Coinfection with other feline pathogens (i.e. feline leukaemia virus, feline immunodeficiency virus, feline Coronavirus, Leishmania and Dirofilaria immitis) could not be detected. This study reveals the presence of H. felis in Austria and provides more evidence on the geographical distribution and pathogenicity of this parasite for domestic cats. To the authors' knowledge, this is the first autochthonous case of feline hepatozoonosis in Central Europe.
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