Evidence map›Paper›PMID 31228561›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2020

Avoidance, Insight, Impairment Recognition Concordance, and Cognitive-Behavioral Therapy Outcomes in Pediatric Obsessive-Compulsive Disorder.

Robert R Selles, Davið R M A Højgaard, Tord Ivarsson, Per Hove Thomsen, Nicole Michelle McBride, Eric A Storch, Daniel Geller, Sabine Wilhelm, Lara J Farrell, Allison M Waters and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

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  16. Symptom Trajectories of Early Responders and Remitters among Youth with OCD.Journal of obsessive-compulsive and related disorders · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 5 countries.

Robert R SellesUniversity of British Columbia and BC Children's Hospital, Vancouver, BC, Canada. Electronic address: rselles@bcchr.ca.
Davið R M A HøjgaardAarhus University Hospital, Denmark.
Tord IvarssonUniversity of Gothenburg, Sweden.
Per Hove ThomsenAarhus University Hospital, Denmark.
Nicole Michelle McBrideUniversity of Arkansas for Medical Sciences, Little Rock.
Eric A StorchBaylor College of Medicine, Houston, TX.
Daniel GellerHarvard Medical School and Massachusetts General Hospital, Boston, MA.
Sabine WilhelmHarvard Medical School and Massachusetts General Hospital, Boston, MA.
Lara J FarrellGriffith University, Queensland, Australia.
Allison M WatersGriffith University, Queensland, Australia.
Sharna MathieuGriffith University, Queensland, Australia.
S Evelyn StewartUniversity of British Columbia and BC Children's Hospital, Vancouver, BC, Canada.
Griffith University · AUAarhus University Hospital · DKHarvard University · USBaylor College of Medicine · USBC Children's Hospital · CAUniversity of Arkansas for Medical Sciences · USUniversity of British Columbia · CAUniversity of Gothenburg · SE

Funding

2/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093402 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI GELLER, DANIEL A · 2011 to 2014
$1.7M
1/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093381 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI STORCH, ERIC A. · 2011 to 2014
$1.2M
NIMH NIH HHS R01 MH093381NIMH NIH HHS R01 MH093402
6 · The paper itself

Abstract

objectiveInsight and avoidance are commonly discussed factors in obsessive-compulsive disorder (OCD) that have demonstrated associations with increased severity as well as reduced treatment response in adults, but these factors have not been sufficiently examined in pediatric OCD. This study examined the impacts of avoidance, insight, and impairment recognition concordance on cognitive-behavioral therapy (CBT) outcomes as well as impacts of CBT on insight and avoidance in a large sample of youths affected by OCD.

methodData from 573 OCD-affected youths enrolled in CBT trials were aggregated. Children's Yale-Brown Obsessive-Compulsive Scale items measured treatment response, insight, and avoidance. Standardized differences between child and parent ratings of impairment were used to calculate impairment recognition concordance. Binary logistic regression was used to identify variables associated with treatment response.

resultsGreater avoidance, limited child recognition of impairment, older age, and lower baseline severity predicted reduced likelihood of treatment response, but insight did not. Both insight and avoidance improved significantly following CBT. Response rates were lower when posttreatment insight and avoidance were worse.

conclusionContrasting with prevailing belief, poor insight does not appear to limit CBT response potential in pediatric OCD. Avoidance and impairment recognition are understudied CBT response predictors and warrant further consideration in pediatric OCD. Clinicians should attend to these factors to optimize outcomes for children affected by this common, debilitating illness.

Indexed as

Cognitive Behavioral TherapyObsessive-Compulsive DisorderAdolescentAdultAgedChildCognitionFamilyHumansRecognition, PsychologyTreatment Outcomeexposure and response preventionmega-analysispredictorssymptom recognitiontreatment response

Identifiers

PMID31228561
PMCPMC7179819
OpenAlexW2952437500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.