Evidence map›Paper›PMID 31228560›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2020

Mechanisms of Change in the Prevention of Depression: An Indicated School-Based Prevention Trial at the Transition to High School.

Jennifer B Blossom, Molly C Adrian, Ann Vander Stoep, Elizabeth McCauley

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00071513 (Middle School to High School Transition Project), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00071513 phase1completednot on this map

Middle School to High School Transition Project

TypeinterventionalSponsorUniversity of WashingtonRan2003 to 2007Enrolled497ConditionsDepression, Substance-Related DisordersArmsCAST-T/HSTS, Brief Intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer B BlossomUniversity of Washington School of Medicine, Seattle; Seattle Children's Hospital, WA. Electronic address: jblossom@uw.edu.
Molly C AdrianUniversity of Washington School of Medicine, Seattle; Seattle Children's Hospital, WA.
Ann Vander StoepUniversity of Washington School of Medicine, Seattle.
Elizabeth McCauleyUniversity of Washington School of Medicine, Seattle; Seattle Children's Hospital, WA.

Funding

Middle School to High School Transition ProjectR01MH061984 · NIMH · UNIVERSITY OF WASHINGTON · PI MCCAULEY, ELIZABETH · 2002 to 2006
$2.1M
NIMH NIH HHS R01 MH061984
6 · The paper itself

Abstract

objectiveDepression represents a major public health concern, and prevalence increases significantly during adolescence. The high school transition may exacerbate the risk of depression for youth with pre-existing vulnerability. The High School Transition Program (HSTP) is a brief, skills-based intervention that has demonstrated efficacy in preventing depression in adolescents. The current study aimed to evaluate the theorized mechanisms of change of the HSTP intervention by testing a multiple mediation model including school attachment (SA) and self-esteem (SE) as two mediators of treatment outcomes.

methodStudents (N= 497; 61.5% girls) with elevated depressive symptoms, identified for the intervention program via an eighth-grade screening, were randomized to a brief intervention (n = 247) or the HSTP (n = 233) from 2003 to 2008. Participants completed measures at five time points. The first assessment occurred at the start of the second semester of eighth grade and the last assessment occurred at the end of ninth grade. A multiple mediation model tested whether SA and SE contributed to changes in depression for youth in the HSTP.

resultsThe mediation model, including contemporaneously assessed SE and SA, was not supported. There was evidence of sequential mediation, such that students who participated in the HSTP intervention reported higher SA, which in turn predicted improved SE, and in turn contributed to amelioration of depressive symptoms.

conclusionThe HSTP intervention ameliorated depressive symptoms by targeting factors specific to the school transition (ie, SA). Results suggest youth at risk for depression may benefit from prevention efforts that enhance students' capacity to effectively manage identified environmental stressors, such as school transitions. CLINICAL TRIAL REGISTRATION INFORMATION: Middle School to High School Transition Project: Depression and Substance Abuse Prevention; https://clinicaltrials.gov/; NCT00071513.

Indexed as

DepressionSchool Health ServicesAdolescentFemaleHumansSchoolsSelf ConceptStudentsadolescent depressionmechanisms of changepreventionschool-based mental health

Identifiers

PMID31228560
PMCPMC6920576

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.