Evidence map›Paper›PMID 31228296›Full record

ArticleMagnetic resonance in medicine2019

3D nonrigid motion correction for quantitative assessment of hepatic lesions in DCE-MRI.

Matteo Ippoliti, Mathias Lukas, Winfried Brenner, Tobias Schaeffter, Marcus R Makowski, Christoph Kolbitsch

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Bulk motion-compensated DCE-MRI for functional imaging of kidneys in newborns.Journal of magnetic resonance imaging : JMRI · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matteo IppolitiDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-3019-7647
Mathias LukasDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Winfried BrennerDepartment of Nuclear Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Tobias SchaeffterPhysikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany.
Marcus R MakowskiDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Christoph KolbitschPhysikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany.ORCID 0000-0002-4355-8368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide nonrigid respiratory motion-corrected DCE-MRI images with isotropic resolution of 1.5 mm, full coverage of abdomen, and covering the entire uptake curve with a temporal resolution of 6 seconds, for the quantitative assessment of hepatic lesions.

methods3D DCE-MRI data were acquired at 3 T during free breathing for 5 minutes using a 3D T

resultsRespiratory motion produced artifacts and misalignment between dynamic volumes (lesion average motion amplitude of 3.82 ± 1.11 mm). Motion correction minimized artifacts and improved average contrast-to-noise ratio of hepatic lesions in late phase by 47% (p < .01). Quantitative endothelial permeability maps of motion-corrected data demonstrated enhanced visibility of different pathologies (e.g., metastases, hemangiomas, cysts, necrotic tumor substructure) and showed improved contrast-to-noise ratio by 62% (p < .01) compared with uncorrected data.

conclusion3D nonrigid motion correction in DCE-MRI improves both visual and quantitative assessment of hepatic lesions by ensuring accurate alignment between 3D DCE images and reducing motion blurring. This approach does not require breath-holds and minimizes scan planning by using a large FOV with isotropic resolution.

Indexed as

ArtifactsContrast MediaFemaleGadolinium DTPAHumansImage EnhancementImage Processing, Computer-AssistedImaging, Three-DimensionalLiver DiseasesMagnetic Resonance ImagingMaleMiddle AgedMotionContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPADCEGRPEhepatic lesionmotion correctionpermeability

Identifiers

PMID31228296
PMCPMC6771884

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.