Evidence map›Paper›PMID 31228293›Full record

ArticleMagnetic resonance in medicine2019

Comparison of gadolinium-enhanced and ferumoxytol-enhanced conventional and UTE-MRA for the depiction of the pulmonary vasculature.

Gesine Knobloch, Timothy Colgan, Mark L Schiebler, Kevin M Johnson, Geng Li, Tilman Schubert, Scott B Reeder, Scott K Nagle

Open access · greenAbstract readComparative Study
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Imaging in chronic thromboembolic pulmonary hypertension: review of the current literature.Diagnostic and interventional radiology (Ankara, Turkey) · 2026
    Review
  2. Review
  3. Ferumoxytol-enhanced cardiovascular magnetic resonance imaging: applications and technical advances.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Review
  4. Review
  5. Review
  6. Article
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  13. Do We Swallow the Waste From Our Brain?Frontiers in neuroscience · 2021
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 3 countries.

Gesine KnoblochDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0002-9594-7680
Timothy ColganDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0002-4400-7525
Mark L SchieblerDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.
Kevin M JohnsonDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.
Geng LiDepartment of Biostatistics and Medical Informatics, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.
Tilman SchubertDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.
Scott B ReederDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.
Scott K NagleDepartment of Radiology, University of Wisconsin-School of Medicine and Public Health, Madison, Wisconsin.
University of Wisconsin–Madison · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
MRI methods for high resolution imaging of the lungR01HL136965 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, KEVIN MICHAEL, LARSON, PEDER ERIC ZUFALL · 2018 to 2021
$2.7M
Confounder-Corrected Quantitative MRI Biomarkers of HepaticR01DK100651 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2017
$2.7M
Evolution of Quantitative MRI Biomarkers of Metabolic Syndrome During PubertyK24DK102595 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2018
$927k
NCATS NIH HHS UL1 TR002373NCI NIH HHS T32 CA009206NHLBI NIH HHS R01 HL136965NIDDK NIH HHS K24 DK102595NIDDK NIH HHS R01 DK100651
6 · The paper itself

Abstract

purposeTo evaluate the feasibility of ferumoxytol (FE)-enhanced UTE-MRA for depiction of the pulmonary vascular and nonvascular structures.

methodsTwenty healthy volunteers underwent contrast-enhanced pulmonary MRA at 3 T during 2 visits, separated by at least 4 weeks. Visit 1: The MRA started with a conventional multiphase 3D T

resultsFlip angle in the range of 18°-24° resulted in best T

conclusionFree-breathing UTE-MRA using FE is feasible for simultaneous assessment of the pulmonary vasculature and nonvascular structures. Patient studies should investigate the clinical utility of free-breathing UTE-MRA for assessment of pulmonary emboli.

Indexed as

Ferrosoferric OxideOrganometallic CompoundsAdultContrast MediaFeasibility StudiesFemaleHealthy VolunteersHumansImage EnhancementImage Processing, Computer-AssistedImaging, Three-DimensionalLungMagnetic Resonance AngiographyMaleMeglumineProspective StudiesContrast MediaFerrosoferric Oxidegadobenic acidMeglumineOrganometallic Compoundsferumoxytolgadobenate dimegluminemagnetic resonance angiographypulmonary MRAultrashort echo time

Identifiers

PMID31228293
PMCPMC6660410
OpenAlexW2952862986

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.