Evidence map›Paper›PMID 31228162›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Rat Models of Metabolic Syndrome.

Anne E Kwitek

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Dual ETFundamental & clinical pharmacology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Metabolic Syndrome: Lessons from Rodent andBioMed research international · 2022
    Review
  15. Article
  16. Methods for the ComprehensiveFrontiers in physiology · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anne E KwitekDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA. akwitek@mcw.edu.

Funding

RAT GENOME DATABASER01HL064541 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ANNE E. KWITEK · 1999 to 2026
$50.0M
Dissecting the genetics of the Metabolic Syndrome on Chromosome 17 of the LH ratR01HL089895 · NHLBI · UNIVERSITY OF IOWA · PI KWITEK, ANNE E. · 2008 to 2012
$1.7M
Identification of a metabolic syndrome transcriptome signature in the LH ratR21DK089417 · NIDDK · UNIVERSITY OF IOWA · PI KWITEK, ANNE E., XING, YI · 2010 to 2011
$411k
NHLBI NIH HHS R01 HL064541NHLBI NIH HHS R01 HL089895NIDDK NIH HHS R21 DK089417
6 · The paper itself

Abstract

Metabolic syndrome is a complex disorder that comprises several other complex disorders, including obesity, hypertension, dyslipidemia, and diabetes. There are several rat models that encompass component features of MetS. Some models are inbred strains selected for one or more traits underlying MetS; others are population models with genetic risk for MetS traits, are induced by environmental stressors such as diet, are spontaneous monogenic mutant models, or are congenic strains derived from a combination of these models. Together they can be studied to identify the genetic and physiological underpinnings of MetS to identify candidate genes or mechanisms for study in human MetS subjects.

Indexed as

Disease Models, AnimalAnimalsCholesterolGenetic Predisposition to DiseaseLipoproteins, HDLMetabolic SyndromeRatsRats, Inbred StrainsCholesterolLipoproteins, HDLHypertensionMetabolic syndromeMetSObesityRat disease modelRat genetic modelRat inbred model

Identifiers

PMID31228162
PMCPMC7315404

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.