Evidence map›Paper›PMID 31228044›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2020

Peritoneal metastasis in gastric cancer: results from the German database.

Beate Rau, Andreas Brandl, Pompiliu Piso, Jörg Pelz, Peter Busch, Cedric Demtröder, Silke Schüle, Hans-Jürgen Schlitt, Marc Roitman, Jürgen Tepel and 9 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 5 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 5 syntheses or guidelines pooled it, 126 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Review
  8. Role of surgery in metastatic gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  9. Review
  10. Review
  11. POSTNFrontiers in immunology · 2026
    Article
  12. Article
  13. Gastric cancer with limited peritoneal metastasis: Role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 1 country.

Beate RauDepartment of Surgery, Campus Virchow-Klinikum and Charité Campus Mitte, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. beate.rau@charite.de.ORCID http://orcid.org/0000-0001-5820-6907
Andreas BrandlDepartment of Surgery, Campus Virchow-Klinikum and Charité Campus Mitte, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Pompiliu PisoDepartment of General and Visceral Surgery, Barmherzige Brueder Hospital Regensburg, Regensburg, Germany.
Jörg PelzDepartment of General, Visceral, and Oncologic Surgery, St. Bernward Hospital, Hildesheim, Germany.
Peter BuschDepartment of Visceral, General Surgery, Agatharied Hospital, Hausham, Germany.
Cedric DemtröderDepartment of General Surgery and Therapy Center for Peritoneal Carcinomatosis, Marien Hospital Herne, Ruhr-Universität Bochum, Herne, Germany.
Silke SchüleDepartment of General, Visceral and Vascular Surgery, University Hospital of Jena, Jena, Germany.
Hans-Jürgen SchlittDepartment of Surgery, University Hospital Regensburg, Regensburg, Germany.
Marc RoitmanSurgical Center and Asklepios Tumor Center, Asklepios Paulinen Klinik, Wiesbaden, Germany.
Jürgen TepelClinic for General, Thoracic and Visceral Surgery, Klinikum Osnabrück, Osnabrück, Germany.
Udo SulkowskiDepartment of General, Visceral and Vascular Surgery, Clemenshospital, Münster, Germany.
Faik UzunogluDepartment of General, Visceral and Thoracic Surgery, University Medical Centre, Hamburg-Eppendorf, Hamburg, Germany.
Michael HünerbeinDepartment of General, Visceral and Cancer Surgery, HELIOS Klinikum Berlin-Buch, Berlin, Germany.
Rüdiger HörbeltDepartment of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital Gießen, Gießen, Germany.
Michael StröhleinDepartment of Abdominal, Vascular and Transplant Surgery, Cologne-Merheim Medical Center, Witten/Herdecke University, Cologne, Germany.
Stefan BeckertDepartment of Surgery, Comprehensive Cancer Center, University of Tübingen, Tübingen, Germany.
Ingmar KönigsrainerDepartment of Surgery, Comprehensive Cancer Center, University of Tübingen, Tübingen, Germany.
Alfred KönigsrainerDepartment of Surgery, Comprehensive Cancer Center, University of Tübingen, Tübingen, Germany.
Peritoneum Surface Oncology Group and members of the StuDoQ|Peritoneum Registry of the German Society for General and Visceral Surgery (DGAV)
University of Tübingen · DECharité - Universitätsmedizin Berlin · DEUniversität Hamburg · DEUniversitätsklinik Marien Hospital Herne · DEUniversity Hospital Regensburg · DEWitten/Herdecke University · DEAsklepios Fachklinikum Brandenburg · DEClemenshospital Münster · DEKrankenhaus Agatharied · DEKrankenhaus Barmherzige Brüder · DESt. Bernward Krankenhaus · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with peritoneal metastases of gastric cancer have a poor prognosis with a median survival of 7 months. A benefit of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) could be shown in several selected patient cohorts but remains controversial. The aim of this study was, to reflect the results of a national German HIPEC registry initiated by the German Society of General and Visceral Surgery (DGAV).

methodsThe DGAV HIPEC registry StuDoQ|Peritoneum documents patients with peritoneal malignancy contributed from 52 hospitals. All consecutive documented patients from 2011 until 2016 (n = 3078) were treated with CRS and HIPEC and were analysed. A total of 315 (10%) suffered from gastric cancer and were analysed.

resultsA complete data set of 235 patients was available for this study, including 113 male (48.1%) and 122 female (51.9%) patients with a median age of 53.4 years (SD ± 11.9). The median PCI was 8.0 (range 1-30). A complete cytoreduction was achieved in 121 patients (71.6%). Postoperative complications (Clavien-Dindo grades 3-4) occurred in 40 patients (17%). The median overall survival (OS) time was 13 months. The 5-year survival rate was 6%. According to the PCI from 0-6 (n = 74); 7-15 (n  = 70) and 16-39 (n = 24) the median OS differs significantly (18 months vs. 12 months vs. 5 months; p = 0.002).

conclusionsCRS and HIPEC in selected patients with gastric cancer and peritoneal spread can improve survival when they are treated in centers. An accurate staging and patient selection are of major importance to achieve long-term survival.

Indexed as

AdultAntineoplastic AgentsCytoreduction Surgical ProceduresDatabases, FactualFemaleGermanyHumansLength of StayMaleMiddle AgedPeritoneal NeoplasmsPostoperative ComplicationsStomach NeoplasmsSurvival RateAntineoplastic AgentsCytoreductive surgeryGastric cancerHyperthermic intraperitoneal chemotherapyPeritoneal metastases

Identifiers

PMID31228044
OpenAlexW2949206562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.