ReviewJournal of thrombosis and thrombolysis2019
A narrative review of red blood cell distribution width as a marker for pulmonary embolism.
Review in Journal of thrombosis and thrombolysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The prevalence and clinical features of pulmonary embolism in patients with AE-COPD: A meta-analysis and systematic review.PloS one · 2021Pooled it
- Predictive modeling for mortality risk in elderly patients with pulmonary embolism using machine learning algorithms.Frontiers in medicine · 2026Article
- Red Cell Distribution Width (RDW), Platelets and Platelet Index MPV/PLT Ratio as Specific Time Point Predictive Variables of Survival Outcomes in COVID-19 Hospitalized Patients.Journal of clinical medicine · 2025Article
- Clinical characteristics and risk factor analysis of overlapping syndromes of COPD-OSA with metabolic syndrome in middle-to-high altitude areas.Frontiers in medicine · 2025Review
- Clinical characteristics, clinical laboratories, and risk factors of elderly patients with chronic obstructive pulmonary disease complicated with pulmonary embolism.Frontiers in medicine · 2025Article
- Associations of RBC counts and incidence of DVT in patients with spinal cord injury: a five year observational retrospective study.Journal of orthopaedic surgery and research · 2024Observational
- Assessment of the CLOT (children's likelihood of thrombosis) real-time risk prediction model of hospital-associated venous thromboembolism in children with congenital heart disease.American heart journal · 2024Article
- Discrimination of the acute pulmonary embolism subtypes based on the novel MAPH score.Journal of thrombosis and thrombolysis · 2024Article
- Association of red cell distribution width/albumin ratio and in hospital mortality in patients with atrial fibrillation base on medical information mart for intensive care IV database.BMC cardiovascular disorders · 2024Article
- Construction and validation of risk prediction models for pulmonary embolism in hospitalized patients based on different machine learning methods.Frontiers in cardiovascular medicine · 2024Article
- Prevalence and Risk Factors of Pulmonary Embolism in COPD Patients Complicated with Secondary Polycythemia.International journal of chronic obstructive pulmonary disease · 2024Article
- Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19.Advances in experimental medicine and biology · 2023Article
- Nomogram for Predicting Postoperative Portal Venous Systemic Thrombosis in Patients with Cirrhosis Undergoing Splenectomy and Esophagogastric Devascularization.Canadian journal of gastroenterology & hepatology · 2022Article
- Preoperative hemoglobin-to-red cell distribution width ratio as a prognostic factor in pulmonary large cell neuroendocrine carcinoma: a retrospective cohort study.Annals of translational medicine · 2022Article
- Blood Cells and Venous Thromboembolism Risk: A Two-Sample Mendelian Randomization Study.Frontiers in cardiovascular medicine · 2022Article
- Prediction of venous thromboembolism with machine learning techniques in young-middle-aged inpatients.Scientific reports · 2021Article
- Article
- ΔRDW: A Novel Indicator with Predictive Value for the Diagnosis and Treatment of Multiple Diseases.International journal of general medicine · 2021Review
- Predictive Value of Red Blood Cell Distribution Width in Poststroke Depression.Computational and mathematical methods in medicine · 2021Observational
- Risk of Stroke in Patients With Patent Foramen Ovale Who Had Pulmonary Embolism.Journal of clinical medicine research · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Red blood cell distribution width (RDW) is a marker of variability in red blood cell size, and is routinely reported as part of a patient's complete blood count. RDW has been shown to be associated with the prediction, severity and prognosis of pulmonary embolism (PE) in recent studies. The underlying biomolecular mechanism of the relationship of RDW to PE is largely unknown, but is thought to be due to the relationship of RDW with acute inflammatory markers and variations in blood viscosity. This review substantiates that a high RDW level, defined using either an arbitrary number or according to receiver operator curve statistics, is associated with a higher risk of acute PE, increased severity (massive vs. submassive) of PE and increased mortality in patients with PE. Nevertheless, the comparison of current studies is limited due to the definition of high RDW (each study uses a different RDW cutoff level), the broad range of exclusion criteria and the inclusion of differing modalities used to diagnose a PE (computed tomography angiogram, ventilation-perfusion study, or clinical diagnosis). Despite the above limitations, these studies provide a promising future clinical use for RDW as a marker of PE.
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