Evidence map›Paper›PMID 31227839›Full record

SynthesisInternational urogynecology journal2019

The negative effect of urologic chronic pelvic pain syndrome on female sexual function: a systematic review and meta-analysis.

Yupeng Guan, Gang Yu, Guoren Wang, Zhiming Bai

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Cheek acupuncture therapy combined with Chinese herbal medicine for female chronic pelvic pain: a retrospective study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yupeng GuanDepartment of Urology, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, No.43, Renmin Avenue, Meilan District, Haikou City, 570208, Hainan Province, China.
Gang YuDepartment of Urology, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, No.43, Renmin Avenue, Meilan District, Haikou City, 570208, Hainan Province, China.
Guoren WangDepartment of Urology, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, No.43, Renmin Avenue, Meilan District, Haikou City, 570208, Hainan Province, China.
Zhiming BaiDepartment of Urology, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, No.43, Renmin Avenue, Meilan District, Haikou City, 570208, Hainan Province, China. hkbzm2018@aliyun.com.
Central South University · CNHainan University · CN

Funding

Natural Science Foundation of Hainan Province (CN) 20158296
6 · The paper itself

Abstract

introduction and hypothesisTo explore the effect of urologic chronic pelvic pain syndrome (UCPPS) on female sexual function.

methodsDatabase searches were conducted in PubMed, EMBASE, the Cochrane Library, and Google Scholar for published literature using the Female Sexual Function Index (FSFI) or reporting the prevalence of dyspareunia. Data extraction and quality evaluation were performed on the literature that met the inclusion criteria, and a meta-analysis was performed using STATA 12.0 and RevMan5.3 software to calculate the mean differences (MD) and odds ratios (OR) and their 95% confidence intervals (CI).

resultsA total of nine case-control studies enrolling 4965 subjects were investigated. The present meta-analysis results demonstrated a strong correlation between UCPPS and dyspareunia (OR = 11.27, 95% CI: 5.15-24.67, P < 0.00001). The UCPPS group had significantly lower scores in each domain of the FSFI compared with the healthy control group: total score (MD = -11.35, 95% CI: -14.54- - 8.16, P < 0.00001); desire (MD = -1.04, 95% CI: -1.20- - 0.88, P < 0.00001); arousal (MD = -1.78, 95% CI: -2.36- - 1.20, P < 0.00001); lubrication (MD = -2.11, 95% CI: -2.49- - 1.73, P < 0.00001); orgasm (MD = -1.50, 95% CI: -1.72- - 1.28, P < 0.00001); satisfaction (MD = -1.54, 95% CI: -1.97- - 1.12, P < 0.00001); pain (MD = -2.89, 95% CI: -3.63- - 2.14, P < 0.00001).

conclusionsUCPPS had a significantly negative effect on female sexual function, particularly in the lubrication, pain, and total score domains. In addition, UCPPS patients had a significantly higher risk of dyspareunia. Psychosocial variables may be a potential pathogenesis of female sexual dysfunction (FSD). Future well-designed research is called for to develop a comprehensive estimate of the association between UCPPS and FSD.

Indexed as

Chronic PainFemaleHumansPelvic PainSexual Dysfunction, PhysiologicalDyspareuniaFemale sexual dysfunctionFemale Sexual Function IndexMeta-analysisUrologic chronic pelvic pain syndrome

Identifiers

PMID31227839
OpenAlexW2951005561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.