Evidence map›Paper›PMID 31227823›Full record

ArticleNature protocols2019

Using DeepLabCut for 3D markerless pose estimation across species and behaviors.

Tanmay Nath, Alexander Mathis, An Chi Chen, Amir Patel, Matthias Bethge, Mackenzie Weygandt Mathis

Abstract read
PubMed Publisher
In one paragraph

Article in Nature protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 743 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
743citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

743 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Deep Learning-Based Quantification of Spontaneous Pain Behaviours in Mice.European journal of pain (London, England) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Lasting aversive consequences of a single dose of 4-hydroxytamoxifen.bioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. PSD-95 drives binocular vision maturation critical for predation.bioRxiv : the preprint server for biology · 2026
    Article
  15. Article
  16. Asymmetrical modulation of fear expression via GABAProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

683 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tanmay NathRowland Institute at Harvard, Harvard University, Cambridge, MA, USA.
Alexander MathisRowland Institute at Harvard, Harvard University, Cambridge, MA, USA.
An Chi ChenDepartment of Electrical Engineering, University of Cape Town, Cape Town, South Africa.
Amir PatelDepartment of Electrical Engineering, University of Cape Town, Cape Town, South Africa.
Matthias BethgeTübingen AI Center & Centre for Integrative Neuroscience, Eberhard Karls Universität Tübingen, Tübingen, Germany.
Mackenzie Weygandt MathisRowland Institute at Harvard, Harvard University, Cambridge, MA, USA. mackenzie@post.harvard.edu.ORCID http://orcid.org/0000-0001-7368-4456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive behavioral tracking of animals during experiments is critical to many scientific pursuits. Extracting the poses of animals without using markers is often essential to measuring behavioral effects in biomechanics, genetics, ethology, and neuroscience. However, extracting detailed poses without markers in dynamically changing backgrounds has been challenging. We recently introduced an open-source toolbox called DeepLabCut that builds on a state-of-the-art human pose-estimation algorithm to allow a user to train a deep neural network with limited training data to precisely track user-defined features that match human labeling accuracy. Here, we provide an updated toolbox, developed as a Python package, that includes new features such as graphical user interfaces (GUIs), performance improvements, and active-learning-based network refinement. We provide a step-by-step procedure for using DeepLabCut that guides the user in creating a tailored, reusable analysis pipeline with a graphical processing unit (GPU) in 1-12 h (depending on frame size). Additionally, we provide Docker environments and Jupyter Notebooks that can be run on cloud resources such as Google Colaboratory.

Indexed as

SoftwareVideo RecordingAlgorithmsAnimalsBehavior, AnimalHumansImaging, Three-DimensionalProgramming LanguagesUser-Computer InterfaceWorkflow

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.