Evidence map›Paper›PMID 31227801›Full record

ArticleMolecular psychiatry2021

Do ADHD-impulsivity and BMI have shared polygenic and neural correlates?

Edward D Barker, Alex Ing, Francesca Biondo, Tianye Jia, Jean-Baptiste Pingault, Ebba Du Rietz, Yuning Zhang, Barbara Ruggeri, Tobias Banaschewski, Sarah Hohmann and 25 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 14 institutions in 6 countries.

Edward D Barker *Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. ted.barker@kcl.ac.uk.
Alex Ing *Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Francesca BiondoInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0001-9952-0249
Tianye JiaInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0001-5399-2953
Jean-Baptiste PingaultDivision of Psychology & Language Sciences, University College London, London, UK.
Ebba Du RietzInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Yuning ZhangInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Barbara RuggeriInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Tobias BanaschewskiDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany.
Sarah HohmannDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany.
Arun L W BokdeDiscipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
Uli BrombergUniversity Medical Centre Hamburg-Eppendorf, House W34, 3.OG, Martinistr. 52, 20246, Hamburg, Germany.
Christian BüchelUniversity Medical Centre Hamburg-Eppendorf, House W34, 3.OG, Martinistr. 52, 20246, Hamburg, Germany.
Erin Burke QuinlanInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0003-2927-1632
Edmund Sounga-BarkeInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
April B BowlingSchool of Health Science, Merrimack College, 315 Turnpike Street North Andover, North Andover, MA, 01845, USA.
Sylvane DesrivièresInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-9120-7060
Herta FlorDepartment of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, Mannheim, Germany.
Vincent FrouinDepartment of Psychology, School of Social Sciences, University of Mannheim, 68131, Mannheim, Germany.ORCID http://orcid.org/0000-0001-9360-6623
Hugh GaravanDepartments of Psychiatry and Psychology, University of Vermont, 05405, Burlington, VT, USA.
Philip AshersonInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Penny GowlandSir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK.
Andreas HeinzCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany.
Bernd IttermannPhysikalisch-Technische Bundesanstalt (PTB), Abbestr. 2 - 12, Berlin, Germany.
Jean-Luc MartinotInstitut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 "Neuroimaging & Psychiatry", University Paris Sud, University Paris Descartes - Sorbonne Paris Cité; and Maison de Solenn, Paris, France.
Marie-Laure Paillère MartinotInstitut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 "Neuroimaging & Psychiatry", University Paris Sud, University Paris Descartes; Sorbonne Université; and AP-HP, Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, Paris, France.ORCID http://orcid.org/0000-0002-0452-2450
Frauke NeesDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany.
Dimitri Papadopoulos-OrfanosDepartment of Psychology, School of Social Sciences, University of Mannheim, 68131, Mannheim, Germany.ORCID http://orcid.org/0000-0002-1242-8990
Luise PoustkaDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Medical Centre Göttingen, von-Siebold-Str. 5, 37075, Göttingen, Germany.
Michael N SmolkaDepartment of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0001-5398-5569
Nora C VetterDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
Henrik WalterCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charitéplatz 1, Berlin, Germany.ORCID http://orcid.org/0000-0002-9403-6121
Robert WhelanSchool of Psychology and Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0002-2790-7281
Gunter SchumannInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
IMAGEN Consortium
King's College London · GBHeidelberg University · DEUniversity of Mannheim · DEDélégation Paris 5 · FRHumboldt-Universität zu Berlin · DETechnische Universität Dresden · DETrinity College Dublin · IEUniversität Hamburg · DEMerrimack College · USPhysikalisch-Technische Bundesanstalt · DEUniversity College London · GBUniversity of Göttingen · DEUniversity of Nottingham · GBUniversity of Vermont · US

Funding

Department of HealthMedical Research Council G0700704Medical Research Council MR/N000390/1Medical Research Council MR/N027558/1
6 · The paper itself

Abstract

There is an extensive body of literature linking ADHD to overweight and obesity. Research indicates that impulsivity features of ADHD account for a degree of this overlap. The neural and polygenic correlates of this association have not been thoroughly examined. In participants of the IMAGEN study, we found that impulsivity symptoms and body mass index (BMI) were associated (r = 0.10, n = 874, p = 0.014 FWE corrected), as were their respective polygenic risk scores (PRS) (r = 0.17, n = 874, p = 6.5 × 10

Indexed as

Attention Deficit Disorder with HyperactivityBody Mass IndexHumansImpulsive BehaviorMultifactorial InheritanceReward

Identifiers

PMID31227801
PMCPMC7910212
OpenAlexW2951877608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.