Evidence map›Paper›PMID 31227765›Full record

ArticleScientific reports2019

Relationship between serum uric acid and hypertension: a cross-sectional study in Bangladeshi adults.

Nurshad Ali, Shakil Mahmood, Farjana Islam, Shahnaz Rahman, Tangigul Haque, Shiful Islam, Sadaqur Rahman, Nazmul Haque, Golam Mosaib, Rasheda Perveen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nurshad AliDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh. nur_rubd@yahoo.com.ORCID http://orcid.org/0000-0003-1649-0887
Shakil MahmoodDepartment of Biochemistry and Molecular Biology, Gono University and Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, 1344, Bangladesh.
Farjana IslamDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.ORCID http://orcid.org/0000-0001-8274-2021
Shahnaz RahmanDepartment of Biochemistry and Molecular Biology, Gono University and Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, 1344, Bangladesh.
Tangigul HaqueDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.
Shiful IslamDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.ORCID http://orcid.org/0000-0002-1826-6777
Sadaqur RahmanDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.
Nazmul HaqueDepartment of Biochemistry and Molecular Biology, Gono University and Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, 1344, Bangladesh.
Golam MosaibDepartment of Biochemistry and Molecular Biology, Gono University and Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, 1344, Bangladesh.
Rasheda PerveenDepartment of Biochemistry and Molecular Biology, Gono University and Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, 1344, Bangladesh.ORCID http://orcid.org/0000-0001-5078-0453
Farida Adib KhanumDepartment of Biochemistry and Molecular Biology, Gono University and Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, 1344, Bangladesh.
Shahjalal University of Science and Technology · BDGono University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental evidence suggests a causal role of serum uric acid (SUA) in hypertension development. Currently, there are few data available on the association between SUA and hypertension; data from Bangladeshi adults are not available yet. This study evaluated the association of SUA with hypertension among Bangladeshi adults. Blood samples were obtained from 140 males and 115 females and analyzed for SUA and lipid levels. Hypertension was defined as SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg. All participants were divided into four quartiles based on SUA concentrations. Association of SUA with hypertension was evaluated by logistic regression models. The prevalence of hypertension and prehypertension was significantly higher in male (15.4 and 47.6%, respectively) than in the female (5.6 and 33.4%, respectively) subjects (p < 0.01). Males had a higher mean level of SUA (310.7 ± 67.9 µmol/L) than in the females (255.3 ± 69.3 µmol/L) (p < 0.001). Hyperuricemia was prevalent 9.1% in males and 10.3% in females. An increasing trend for hypertension and prehypertension was found in both genders with increasing SUA levels in the quartiles (p < 0.01). SUA levels in the quartiles were positively correlated with blood pressure (p < 0.01). After adjusting for baseline covariates, SUA levels were significantly associated with hypertension (p < 0.01). Findings of this study indicate the significance of maintaining normal SUA level to prevent hypertension.

Indexed as

AdultBangladeshBlood Pressure DeterminationCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedUric AcidYoung AdultUric Acid

Identifiers

PMID31227765
PMCPMC6588567
OpenAlexW2952706218

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.