Evidence map›Paper›PMID 31227761›Full record

ArticleScientific reports2019

Interrogation of the infarcted and salvaged myocardium using multi-parametric mapping cardiovascular magnetic resonance in reperfused ST-segment elevation myocardial infarction patients.

Derek J Hausenloy, Mei Xing Lim, Mervyn H H Chan, Valeria Paradies, Rohin Francis, Tushar Kotecha, Daniel S Knight, Marianna Fontana, Peter Kellman, James C Moon and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cardiovascular magnetic resonance native TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Derek J HausenloyThe Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, London, United Kingdom.
Mei Xing LimNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Mervyn H H ChanNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Valeria ParadiesNational Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.
Rohin FrancisThe Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, London, United Kingdom.
Tushar KotechaNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Daniel S KnightNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Marianna FontanaNational Amyloidosis Centre, University College London, Royal Free Hospital, London, United Kingdom.
Peter KellmanNational Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, USA.
James C MoonThe National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom.
Heerajnarain BulluckThe Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, London, United Kingdom. h.bulluck@gmail.com.ORCID http://orcid.org/0000-0002-1985-1783

Funding

British Heart Foundation CS/14/3/31002British Heart Foundation FS/10/039/28270British Heart Foundation FS/18/21/33447British Heart Foundation (BHF) FS/10/039/28270Department of Health
6 · The paper itself

Abstract

We used multi-parametric cardiovascular magnetic resonance (CMR) mapping to interrogate the myocardium following ST-segment elevation myocardial infarction (STEMI). Forty-eight STEMI patients underwent CMR at 4 ± 2 days. One matching short-axis slice of native T1 map, T2 map, late gadolinium enhancement (LGE), and automated extracellular volume fraction (ECV) maps per patient were analyzed. Manual regions-of-interest were drawn within the infarcted, the salvaged and the remote myocardium. A subgroup analysis was performed in those without MVO and with ≤75% transmural extent of infarct. For the whole cohort, T1, T2 and ECV in both the infarcted and the salvaged myocardium were significantly higher than in the remote myocardium. T1 and T2 could not differentiate between the salvaged and the infarcted myocardium, but ECV was significantly higher in the latter. In the subgroup analysis of 15 patients, similar findings were observed for T1 and T2. However, there was only a trend towards ECV

Indexed as

AgedCohort StudiesFemaleHumansMagnetic Resonance Imaging, CineMaleMiddle AgedST Elevation Myocardial Infarction

Identifiers

PMID31227761
PMCPMC6588689

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.