Evidence map›Paper›PMID 31227759›Full record

ArticleScientific reports2019

Hearing loss in humans drinking tube well water with high levels of iron in arsenic-polluted area.

Tingchao He, Nobutaka Ohgami, Xiang Li, Ichiro Yajima, Reina Negishi-Oshino, Yoko Kato, Kyoko Ohgami, Huadong Xu, Nazmul Ahsan, Anwarul Azim Akhand and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Tingchao HeDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nobutaka OhgamiDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Xiang LiDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ichiro YajimaDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Reina Negishi-OshinoDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yoko KatoDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kyoko OhgamiDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Huadong XuDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nazmul AhsanVoluntary Body for International Health Care in Universities, Nagoya, Japan.
Anwarul Azim AkhandVoluntary Body for International Health Care in Universities, Nagoya, Japan.
Masashi KatoDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan. katomasa@med.nagoya-u.ac.jp.
Nagoya University · JPUniversity of Dhaka · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Well water for drinking with increased levels of iron in arsenic-polluted areas has been reported worldwide. Oral exposure to arsenic has been shown to be associated with hearing loss, while there is no evidence for an association between excessive exposure to iron and hearing loss in humans. In this study, we determined iron and arsenic levels in biological samples and hearing levels by pure tone audiometry (PTA) in subjects in a control area and an arsenic-polluted area in Bangladesh. The iron level in well water in the arsenic-polluted area was significantly higher than that in piped supply water in the control area. Subjects in the polluted area (n = 109), who had higher iron and arsenic levels in hair and toenails than those in subjects in the control area (n = 36), had an increased risk of hearing loss at 8 kHz and 12 kHz after adjustments for age, gender, smoking and BMI. Significant associations of the exposure group with hearing loss at 8 kHz and 12 kHz remained after further adjustment for arsenic levels in toenails and hair. Thus, this pilot study showed that excessive exposure to iron via drinking water is a potential risk for hearing loss in humans.

Indexed as

Water WellsAdultArsenicAudiometry, Pure-ToneBangladeshDrinking WaterFemaleHairHearing LossHumansIronMaleNailsPilot ProjectsROC CurveWater Pollutants, ChemicalArsenicDrinking WaterIronWater Pollutants, Chemical

Identifiers

PMID31227759
PMCPMC6588562
OpenAlexW2952718299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.