Evidence map›Paper›PMID 31227717›Full record

ArticleNature communications2019

Identification of HIV transmitting CD11c

Kirstie M Bertram, Rachel A Botting, Heeva Baharlou, Jake W Rhodes, Hafsa Rana, J Dinny Graham, Ellis Patrick, James Fletcher, Toby M Plasto, Naomi R Truong and 19 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Innate Immune Protection Against HIV in the Female Genital Tract.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Neonatal Fc receptor is a functional receptor for classical human astrovirus.Genes to cells : devoted to molecular & cellular mechanisms · 2024
    Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 11 institutions in 3 countries.

Kirstie M BertramCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Rachel A BottingCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Heeva BaharlouCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Jake W RhodesCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.ORCID http://orcid.org/0000-0001-9507-4894
Hafsa RanaCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
J Dinny GrahamCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Ellis PatrickCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.ORCID http://orcid.org/0000-0002-5253-4747
James FletcherInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
Toby M PlastoCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Naomi R TruongCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Caroline RoyleCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Chloe M DoyleCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.ORCID http://orcid.org/0000-0001-7216-634X
Orion TongCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Najla NasrCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Laith BarnoutiAustralia Plastic Surgery, 185-211, Broadway, Sydney, New South Wales, 2007, Australia.
Mark P KohoutAustralia Plastic Surgery, 185-211, Broadway, Sydney, New South Wales, 2007, Australia.
Andrew J BrooksWestmead Hospital, Westmead, New South Wales, 2145, Australia.
Michael P WinesRoyal North Shore Hospital, Reserve Rd, St Leonards, New South Wales, 2065, Australia.
Peter HaertschBurns Unit, Concord Repatriation General Hospital, Sydney, 2139, New South Wales, Australia.
Jake LimDr Jake Lim PLC, Shop 12, Cnr of Aird & Marsden Street, Parramatta, New South Wales, 2150, Australia.
Martijn P GosselinkCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.ORCID http://orcid.org/0000-0002-6396-3977
Grahame CterctekoCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Jacob D EstesAIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, MD, 21702, USA.
Melissa J ChurchillSchool of Health and Biomedical Sciences, College of Science, Engineering and Health, RMIT University, Melbourne, Victoria, 3001, Australia.
Paul U CameronThe Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, Victoria, 3000, Australia.ORCID http://orcid.org/0000-0002-1906-6945
Eric HunterEmory Vaccine Center, 954 Gatewood Road, Atlanta, GA, 30329, USA.ORCID http://orcid.org/0000-0002-4273-8631
Muzlifah A HaniffaInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.ORCID http://orcid.org/0000-0002-3927-2084
Anthony L CunninghamCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia.
Andrew N HarmanCentre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, New South Wales, 2145, Australia. andrew.harman@sydney.edu.au.ORCID http://orcid.org/0000-0003-1535-1279
The University of Sydney · AUWestmead Hospital · AUConcord Repatriation General Hospital · AUEmory Healthcare · USLeidos (United States) · USNewcastle University · GBNew South Wales Institute of Psychiatry · AUPeter Doherty Institute · AURMIT University · AURoyal North Shore Hospital · AURoyal Victoria Infirmary · GB

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Virologic Correlates of Heterosexual TransmissionR01AI051231 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLEN, TODD M, HUNTER, ERIC · 2002 to 2022
$9.9M
Department of Health | National Health and Medical Research Council (NHMRC) APP1078697
6 · The paper itself

Abstract

Langerhans cells (LC) are thought to be the only mononuclear phagocyte population in the epidermis where they detect pathogens. Here, we show that CD11c

Indexed as

Antigen PresentationCD11c AntigenCells, CulturedDendritic CellsEpidermal CellsEpidermisFemaleHealthy VolunteersHIV-1HIV InfectionsHumansMalePrimary Cell CultureReceptors, CCR5Sialic Acid Binding Ig-like Lectin 3T-LymphocytesCCR5 protein, humanCD11c AntigenCD33 protein, humanReceptors, CCR5Sialic Acid Binding Ig-like Lectin 3

Identifiers

PMID31227717
PMCPMC6588576
OpenAlexW2950389326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.