ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2019
Objective napping, cognitive decline, and risk of cognitive impairment in older men.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
66 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Daytime Napping and Cognitive Health in Older Adults: A Systematic Review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Pooled it
- Napping and cognitive decline: a systematic review and meta-analysis of observational studies.BMC geriatrics · 2022Pooled it
- Benefits and risks of napping in older adults: A systematic review.Frontiers in aging neuroscience · 2022Pooled it
- Daytime naps and depression risk: A meta-analysis of observational studies.Frontiers in psychology · 2022Pooled it
- Physical Activity and Cognitive Function Among Chinese Adults Aged 45 Years and Older with Self-Reported Hearing Loss: A 9-Year Longitudinal Study.Brain and behavior · 2026Observational
- A gradual and sustainable approach to diagnosing sleep and circadian disturbances in dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Breaking the nap habit: one-year nap restriction mitigates memory decline in older adults.GeroScience · 2026Article
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- Distinct roles of chronotype, daytime napping, and sleep duration in biological and functional aging: a univariable and multivariable Mendelian randomization study.Clinical epigenetics · 2026Article
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- Daytime napping and nighttime sleep and motoric cognitive risk syndrome among Chinese older adults: a nationwide cohort study.BMC geriatrics · 2025Observational
- Multidimensional sleep profiles via machine learning and risk of dementia and cardiovascular disease.Communications medicine · 2025Article
- Timing and intraindividual variability of daytime napping and Alzheimer's disease in older adults.Communications medicine · 2025Article
- Five-Year Changes in 24-Hour Sleep-Wake Activity and Dementia Risk in Oldest Old Women.Neurology · 2025Article
- Alpha rhythm and Alzheimer's disease: Has Hans Berger's dream come true?Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Daytime Napping in Adults: Benefits or Risks? Insights from Mendelian Randomization Studies.Current sleep medicine reports · 2025Article
- Naps, night-time sleep and cognitive function among middle-aged and older people in China.PloS one · 2025Article
- Association of sleep duration and sleep quality with cognitive frailty in Chinese older adults.Frontiers in public health · 2025Article
- Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer's disease pathology.Alzheimer's research & therapy · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionLittle is known about the longitudinal association between napping and cognitive impairment in older adults.
methodsWe used wrist actigraphy to measure naps in 2751 community-dwelling older men. Cognition was assessed repeatedly over 12 years, and clinically significant cognitive impairment was determined by physician diagnosis, Alzheimer's medication use or a significant cognitive decline.
resultsAfter adjustment for all covariates, men with longer napping duration had greater cognitive decline and higher risk of cognitive impairment. Men who napped for ≥120 min/day (vs. <30 min/day) were 66% more likely to develop cognitive impairment (odds ratio = 1.66, 95% CI: 1.09-2.54) in 12 years. Further adjustment for nighttime sleep quality did not appreciably alter the results. The association between napping and cognitive impairment was more pronounced among those with higher sleep efficiency and average sleep duration. DISCUSSION: Napping might be useful as an early marker of cognitive impairment in the elderly, and its cognitive effects may differ by nighttime sleep.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.