ArticleNeuron2019
Unusual Physiological Properties of Smooth Monostratified Ganglion Cell Types in Primate Retina.
Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Synaptic Organization of the Primate Retina: Toward a Human Foveal Connectome.Annual review of vision science · 2026Review
- Filter, Detector, Predictor: The expanding repertoire of retinal computation in vertebrates.Vision research · 2026Review
- Surround motion modulates the encoding properties of primate retinal ganglion cells.Cell reports · 2026Article
- Spatiotemporal Immune Dynamics in Experimental Retinal Ganglion Cell Injury Models.Immunity, inflammation and disease · 2025Review
- Decomposition of retinal ganglion cell electrical images for cell type and functional inference.bioRxiv : the preprint server for biology · 2025Article
- Article
- Direct-Print 3D Electrodes for Large-Scale, High-Density, and Customizable Neural Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Cell-type specific repertoire of responses to natural scenes in primate retinal ganglion cells.Frontiers in cellular neuroscience · 2025Article
- Review
- Article
- Fixational eye movements enhance the precision of visual information transmitted by the primate retina.Nature communications · 2024Article
- Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina.bioRxiv : the preprint server for biology · 2024Article
- Spike sorting in the presence of stimulation artifacts: a dynamical control systems approach.Journal of neural engineering · 2024Article
- Population encoding of stimulus features along the visual hierarchy.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Synaptic Origins of the Complex Receptive Field Structure in Primate Smooth Monostratified Retinal Ganglion Cells.eNeuro · 2024Article
- Inferring light responses of primate retinal ganglion cells using intrinsic electrical signatures.Journal of neural engineering · 2023Article
- Diversity of Ganglion Cell Responses to Saccade-Like Image Shifts in the Primate Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Inference of Electrical Stimulation Sensitivity from Recorded Activity of Primate Retinal Ganglion Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- High-Fidelity Reproduction of Visual Signals by Electrical Stimulation in the Central Primate Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Focal electrical stimulation of human retinal ganglion cells for vision restoration.Journal of neural engineering · 2022Article
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9 authors.
Funding
Abstract
The functions of the diverse retinal ganglion cell types in primates and the parallel visual pathways they initiate remain poorly understood. Here, unusual physiological and computational properties of the ON and OFF smooth monostratified ganglion cells are explored. Large-scale multi-electrode recordings from 48 macaque retinas revealed that these cells exhibit irregular receptive field structure composed of spatially segregated hotspots, quite different from the classic center-surround model of retinal receptive fields. Surprisingly, visual stimulation of different hotspots in the same cell produced spikes with subtly different spatiotemporal voltage signatures, consistent with a dendritic contribution to hotspot structure. Targeted visual stimulation and computational inference demonstrated strong nonlinear subunit properties associated with each hotspot, supporting a model in which the hotspots apply nonlinearities at a larger spatial scale than bipolar cells. These findings reveal a previously unreported nonlinear mechanism in the output of the primate retina that contributes to signaling spatial information.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.