ArticleGenome biology2019
Ancient polymorphisms contribute to genome-wide variation by long-term balancing selection and divergent sorting in Boechera stricta.
Article in Genome biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
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27 citing papers in PubMed.
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- Chromosome-level genome assembly of Trichiurus japonicus resolves species boundaries and evolutionary history of cutlassfishes in Northwest Pacific.BMC genomics · 2026Article
- Overdominance for fitness: a genomic comparison between empirical and simulated data with Drosophila melanogaster.Genetics · 2026Article
- Evolutionary Systems Biology Identifies Genetic Trade-offs in Rice Defense against Aboveground and Belowground Attackers.Plant & cell physiology · 2025Article
- Need for Mechanisms to Monitor Ocean Circulation-Driven Seagrass Population Expansions.Ecology and evolution · 2025Article
- Repeated global adaptation across plant species.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Cryptic divergence in and evolutionary dynamics of endangered hybrid Picea brachytyla sensu stricto in the Qinghai-Tibet Plateau.BMC plant biology · 2024Article
- The genetic architecture of repeated local adaptation to climate in distantly related plants.Nature ecology & evolution · 2024Article
- Evolution of the Correlated Genomic Variation Landscape Across a Divergence Continuum in the Genus Castanopsis.Molecular biology and evolution · 2024Article
- Genomic insights into differentiation and adaptation ofEcology and evolution · 2024Article
- Genomics of plant speciation.Plant communications · 2023Review
- Review
- The role of gene presence-absence variations on genetic incompatibility in Asian rice.The New phytologist · 2023Article
- Linked selection, differential introgression and recombination rate variation promote heterogeneous divergence in a pair of yellow croakers.Molecular ecology · 2022Article
- A possible genomic footprint of polygenic adaptation on population divergence in seed beetles?Ecology and evolution · 2022Article
- Genomic insights into zokors' phylogeny and speciation in China.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Globally Relaxed Selection and Local Adaptation in Boechera stricta.Genome biology and evolution · 2022Article
- Patterns of genomic divergence in sympatric and allopatric speciation of three Mihoutao (Horticulture research · 2022Article
- Adaptive Introgression Facilitates Adaptation to High Latitudes in European Aspen (Populus tremula L.).Molecular biology and evolution · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
Abstract
backgroundGenomic variation is widespread, and both neutral and selective processes can generate similar patterns in the genome. These processes are not mutually exclusive, so it is difficult to infer the evolutionary mechanisms that govern population and species divergence. Boechera stricta is a perennial relative of Arabidopsis thaliana native to largely undisturbed habitats with two geographic and ecologically divergent subspecies. Here, we delineate the evolutionary processes driving the genetic diversity and population differentiation in this species.
resultsUsing whole-genome re-sequencing data from 517 B. stricta accessions, we identify four genetic groups that diverged around 30-180 thousand years ago, with long-term small effective population sizes and recent population expansion after the Last Glacial Maximum. We find three genomic regions with elevated nucleotide diversity, totaling about 10% of the genome. These three regions of elevated nucleotide diversity show excess of intermediate-frequency alleles, higher absolute divergence (d
conclusionsOur results suggest that long-term balancing selection on disease resistance genes may have maintained ancestral haplotypes across different geographical lineages, and unequal sorting of balanced polymorphisms may have generated genomic regions with elevated divergence. This study highlights the importance of ancestral balanced polymorphisms as crucial components of genome-wide variation.
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