ArticleArthritis research & therapy2019
Concurrent validity of provisional remission criteria for gout: a dual-energy CT study.
Article in Arthritis research & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Baseline Dual-Energy Computed Tomography Urate Volume Predicts Fulfillment of Gout Remission After Two Years of Urate-Lowering Therapy.Arthritis care & research · 2024Trial
- Delineating circulating lymphocyte subsets in the transition from gout remission to recurrence.Frontiers in immunology · 2025Article
- The Patient Experience of Gout Remission: A Qualitative Study.ACR open rheumatology · 2023Article
- Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Profiling of serum oxylipins identifies distinct spectrums and potential biomarkers in young people with very early onset gout.Rheumatology (Oxford, England) · 2023Article
- Real-time and accurate calibration detection of gout stones based on terahertz and Raman spectroscopy.Frontiers in bioengineering and biotechnology · 2023Article
- Disease modification in gout: a qualitative study of gout expert rheumatologists.Rheumatology advances in practice · 2022Article
- Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging.Journal of clinical medicine · 2021Review
- Sonographic estimation of monosodium urate burden predicts the fulfillment of the 2016 remission criteria for gout: a 12-month study.Arthritis research & therapy · 2021Observational
- Defining remission in patients with gout.Nature reviews. Rheumatology · 2019Article
- [What is new on gout? : Report from ACR 2018].Zeitschrift fur Rheumatologie · 2019Article
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6 authors at 4 institutions in 3 countries.
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Abstract
backgroundProvisional gout remission criteria including five domains (serum urate, tophus, flares, pain due to gout, and patient global assessment) have been proposed. The aim of this study was to test the concurrent validity of the provisional gout remission criteria by comparing the criteria with dual-energy CT (DECT) findings.
methodsPatients with gout on allopurinol ≥ 300 mg daily were prospectively recruited into a multicenter DECT study. Participants attended a standardized study visit which recorded gout flare frequency in the preceding 12 months, physical examination for tophus, serum urate, and patient questionnaires. DECT scans of both hands/wrists, feet/ankles/Achilles, and knees were analyzed by two DECT radiologists. The relationship between the DECT urate crystal volume and deposition with individual domains as well as the provisional remission criteria set was analyzed.
resultsThe provisional remission criteria were fulfilled in 23 (15.1%) participants. DECT urate crystal deposition was observed less frequently in those fulfilling the provisional remission criteria (44%), compared with those not fulfilling the criteria (73.6%, odds ratio 0.28, P = 0.004). The median (range) DECT urate crystal volume was 0.00 (0.00-0.46) cm
conclusionsIn people with gout established on allopurinol, a state of remission as defined by the provisional remission criteria is associated with less DECT urate crystal deposition. While this study provides support for the validity of the provisional gout remission criteria, it also demonstrates that some crystal deposition may be present in people achieving these criteria.
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